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Provigil (Modafinil) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (13)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Provigil (Modafinil) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Provigil side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-30

Patient: female, weighing 70.4 kg (154.8 pounds)

Reactions: Abnormal Dreams, Drug Interaction, Hallucination

Drug(s) suspected as cause:
Provigil

Other drugs received by patient possibly interacting with the suspect drug:
Xanax
    Dosage: .5 milligram;
    End date: 2009-06-01

Other drugs received by patient: Prozac; Aspirin; Toprol-XL; Wellbutrin



Possible Provigil side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: male, weighing 82.0 kg (180.4 pounds)

Reactions: Limb Discomfort, Drug Interaction, Hypertension

Drug(s) suspected as cause:
Synthroid
    Dosage: .137 milligram;
    Administration route: Oral
    Indication: Thyroid Disorder
    Start date: 1984-07-01

Provigil
    Dosage: 200 milligram;
    Administration route: Oral
    Indication: Fatigue
    Start date: 2005-01-01

Lipitor
    Dosage: 20 milligram;
    Administration route: Oral
    Indication: Hypercholesterolaemia
    Start date: 1999-01-01

Other drugs received by patient: Rebif



Possible Provigil side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: female

Reactions: Drug Interaction, Hypertension, Hallucination

Drug(s) suspected as cause:
Provigil
    Administration route: Oral

Paxil



Possible Provigil side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: male, weighing 82.0 kg (180.4 pounds)

Reactions: Drug Interaction, Headache, Hypertension

Drug(s) suspected as cause:
Dexedrine
    Dosage: 10 milligram;
    Administration route: Oral
    Indication: Attention Deficit / Hyperactivity Disorder
    Start date: 1997-01-01
    End date: 2007-07-01

Provigil
    Dosage: 200 milligram;
    Administration route: Oral
    Indication: Autoimmune Disorder
    Start date: 2007-06-01



Possible Provigil side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Dystonia, Chills, Therapeutic Response Unexpected, Drug Interaction, Suicidal Ideation, Anxiety, Irritability, Mood Swings, Depression

Drug(s) suspected as cause:
Wellbutrin
    Dosage: 150 milligram;
    Administration route: Oral
    Indication: Depression
    Start date: 2005-01-01

Provigil
    Dosage: 200 milligram;
    Administration route: Oral
    Indication: Multiple Sclerosis
    Start date: 2003-01-01

Cymbalta
    Dosage: 30 milligram;
    Administration route: Oral
    Indication: Depression
    Start date: 2008-05-28
    End date: 2008-05-28

Other drugs received by patient: Synthroid; Aspirin; Multi-Vitamin; Norvasc; Norvasc; Clonazepam



Possible Provigil side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-26

Patient: male, weighing 107.0 kg (235.4 pounds)

Reactions: Paranoia, Ideas of Reference, Drug Interaction

Drug(s) suspected as cause:
Provigil
    Dosage: 200 milligram;
    Administration route: Oral
    Indication: Sleep Apnoea Syndrome
    Start date: 2007-10-02
    End date: 2007-10-15

Requip
    Dosage: .05 milligram;
    Indication: Restless Legs Syndrome
    Start date: 2007-06-01
    End date: 2007-10-15



Possible Provigil side effects in 57 year old female

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: 57 year old female, weighing 68.1 kg (149.8 pounds)

Reactions: Vomiting, Nausea, Drug Interaction, Hallucination

Drug(s) suspected as cause:
Provigil
    Administration route: Oral
    Indication: Depression
    Start date: 2008-12-01

Provigil
    Dosage: 400 milligram;
    Administration route: Oral
    Indication: Depressed Level of Consciousness
    Start date: 1999-01-01
    End date: 2008-10-01

Other drugs received by patient possibly interacting with the suspect drug:
Ephedra

Other drugs received by patient: Wellbutrin; Methadone; Protonix; Levothyroid (Levothyroxine)



Possible Provigil side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: male, weighing 91.0 kg (200.2 pounds)

Reactions: Agitation, Fear, Drug Interaction, Suicidal Ideation, TIC, Insomnia, Depression, Feeling Abnormal, Nervousness

Drug(s) suspected as cause:
Zoloft
    Dosage: 150 milligram;
    Administration route: Oral
    Indication: Depression

Abilify
    Dosage: 10 milligram;
    Administration route: Oral
    End date: 2006-01-01

Abilify
    Dosage: 10 milligram;
    Administration route: Oral
    Start date: 2006-01-01

Provigil
    Dosage: 200 milligram;
    Administration route: Oral
    Indication: Narcolepsy
    Start date: 2005-08-20



Possible Provigil side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-26

Patient: female, weighing 66.0 kg (145.2 pounds)

Reactions: Drug Interaction, Metrorrhagia

Drug(s) suspected as cause:
Provigil
    Dosage: 200mg to 400mg prn
    Administration route: Oral
    Indication: Fatigue
    End date: 2008-01-01

Unspecified Birth Control Pill
    Indication: Oral Contraception



Possible Provigil side effects in female

Reported by a physician from United States on 2012-04-25

Patient: female, weighing 80.0 kg (176.0 pounds)

Reactions: Maternal Exposure During Pregnancy, Drug Interaction, Pregnancy ON Oral Contraceptive, Premature Labour

Drug(s) suspected as cause:
Provigil
    Dosage: 400 milligram;
    Administration route: Oral
    Indication: Narcolepsy
    Start date: 2000-10-02
    End date: 2001-02-01

Oral Contraceptive
    Indication: Contraception

Other drugs received by patient: Allegra; Albuterol



Possible Provigil side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-25

Patient: female, weighing 73.0 kg (160.6 pounds)

Reactions: Psychotic Disorder, Drug Interaction

Drug(s) suspected as cause:
Provigil
    Dosage: 400 milligram;
    Administration route: Oral
    Indication: Narcolepsy
    Start date: 2005-01-01

Effexor
    Dosage: 150 milligram;
    Administration route: Oral
    Start date: 2006-01-01

Provigil
    Indication: Cataplexy

Other drugs received by patient: Imipramine



Possible Provigil side effects in female

Reported by a physician from United States on 2011-12-04

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Migraine, Drug Interaction, Hemiparesis, Vasospasm

Drug(s) suspected as cause:
Ambien
    Administration route: Oral
    Indication: Insomnia

Hydrocodone
    Administration route: Oral
    Indication: Migraine

Celebrex
    Administration route: Oral
    Indication: Migraine

Provigil
    Administration route: Oral
    Indication: Fatigue
    Start date: 2003-02-12
    End date: 2003-02-18

Trileptal
    Administration route: Oral
    Indication: Migraine

Atenolol
    Administration route: Oral
    Indication: Hypotension

Effexor
    Administration route: Oral
    Indication: Hypotension



Possible Provigil side effects in 71 year old male

Reported by a physician from United States on 2011-11-21

Patient: 71 year old male

Reactions: Flushing, Drug Interaction

Drug(s) suspected as cause:
Viibryd
    Dosage: 10 mg (10 mg, 1 in 1 d), oral 20 mg (20 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Depression
    Start date: 2011-07-21

Viibryd
    Dosage: 10 mg (10 mg, 1 in 1 d), oral 20 mg (20 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Depression
    Start date: 2011-07-14
    End date: 2011-07-20

Provigil

Other drugs received by patient: Seroquel (Quetiapine) (Quetiapine); Mirtazapine; Clonazepam

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