Index of reports
> Cases with Diarrhoea (17)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Rapamune (Sirolimus) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Rapamune side effects in 55 year old female
Reported by a consumer/non-health professional from United States on 2012-08-23
Patient: 55 year old female, weighing 90.7 kg (199.5 pounds)
Reactions: Off Label Use, Diarrhoea, Constipation
Drug(s) suspected as cause:
Rapamune
Possible Rapamune side effects in 41 year old male
Reported by a consumer/non-health professional from Brazil on 2012-08-17
Patient: 41 year old male, weighing 71.0 kg (156.2 pounds)
Reactions: Weight Decreased, Diarrhoea, Flatulence, Expired Drug Administered
Drug(s) suspected as cause:
Rapamune
Other drugs received by patient: Ferrous Sulfate; Corus; Prednisone; Angiopril; Myfortic
Possible Rapamune side effects in 11 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-01
Patient: 11 year old female
Reactions: Organising Pneumonia, Post Transplant Lymphoproliferative Disorder, Epstein-Barr Virus Infection, Diarrhoea, Transplant Rejection
Drug(s) suspected as cause:
Rapamune
Indication: Product Used FOR Unknown Indication
Methylprednisolone
Indication: Product Used FOR Unknown Indication
Rituximab
Indication: Post Transplant Lymphoproliferative Disorder
Prednisone
Indication: Product Used FOR Unknown Indication
Mycophenolate Mofetil
Indication: Prophylaxis Against Transplant Rejection
Anti-Thymocyte Globulin NOS
Indication: Product Used FOR Unknown Indication
Tacrolimus
Indication: Product Used FOR Unknown Indication
Azathioprine
Indication: Product Used FOR Unknown Indication
Possible Rapamune side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-31
Patient: female, weighing 72.6 kg (159.6 pounds)
Reactions: Drug Ineffective, Mouth Ulceration, Headache, Rash, Tendon Pain, Joint Swelling, Arthralgia, Diarrhoea, Skin Lesion, Oedema Peripheral, Oedema
Drug(s) suspected as cause:
Rapamune
Dosage: 2 mg, 1x/day
Administration route: Oral
Indication: Lymphangioleiomyomatosis
Start date: 2011-12-08
Tylenol
Dosage: unk
Indication: Headache
Other drugs received by patient: Medroxyprogesterone; Doxycycline
Possible Rapamune side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-23
Patient: female, weighing 63.5 kg (139.7 pounds)
Reactions: Vomiting, Diarrhoea, Nausea, Chronic Obstructive Pulmonary Disease
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rapamune
Other drugs received by patient: Metoprolol; Neurontin; Xanax; Simvastatin; Vitamin B-12; Acetylsalicylic Acid
Possible Rapamune side effects in
Reported by a consumer/non-health professional from United States on 2012-05-22
Patient:
Reactions: Drug Ineffective, Graft Versus Host Disease, Diarrhoea, Infection
Drug(s) suspected as cause:
Mabcampath
Dosage: unk
Indication: Product Used FOR Unknown Indication
Rapamune
Dosage: 1 df, qd
Indication: Product Used FOR Unknown Indication
Enbrel
Dosage: 2 df, 2x/w
Indication: Product Used FOR Unknown Indication
Possible Rapamune side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-15
Patient: female
Reactions: Diarrhoea, Mouth Ulceration, Oedema, Headache, Rash
Drug(s) suspected as cause:
Rapamune
Possible Rapamune side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-11
Patient: female, weighing 72.6 kg (159.6 pounds)
Reactions: Drug Ineffective, Mouth Ulceration, Rash, Headache, Tendon Pain, Joint Swelling, Diarrhoea, Arthralgia, Skin Lesion, Oedema Peripheral, Oedema
Drug(s) suspected as cause:
Tylenol (Caplet)
Dosage: unk
Indication: Headache
Rapamune
Dosage: 2 mg, daily
Indication: Lymphangioleiomyomatosis
Start date: 2011-12-08
Other drugs received by patient: Doxycycline; Medroxyprogesterone
Possible Rapamune side effects in 42 year old male
Reported by a physician from Germany on 2012-05-01
Patient: 42 year old male
Reactions: Diarrhoea, Drug Ineffective, Graft Versus Host Disease, Infection
Drug(s) suspected as cause:
Enbrel
Dosage: 2 df, 2x/week
Indication: Product Used FOR Unknown Indication
Mabcampath
Dosage: unk unk, unk
Rapamune
Dosage: 1 df, 1x/day
Possible Rapamune side effects in 49 year old male
Reported by a physician from Spain on 2012-04-27
Patient: 49 year old male
Reactions: Diarrhoea, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rapamune
Other drugs received by patient possibly interacting with the suspect drug: Mycophenolate Mofetil (Cellcept)
Dosage: 1.25 mg, 1x/day
Prednisolone
Dosage: 15 mg, 1x/day
Administration route: Oral
Indication: Renal Transplant
Start date: 2009-11-01
Mycophenolate Mofetil (Cellcept)
Dosage: 2 g, 1x/day
Administration route: Oral
Indication: Renal Transplant
Start date: 2009-11-01
Septra
Dosage: unk
Administration route: Oral
Indication: Prophylaxis
Start date: 2009-11-01
Other drugs received by patient: Omeprazole; Leucovorin Calcium; Cardura
Possible Rapamune side effects in 42 year old male
Reported by a physician from Germany on 2012-04-24
Patient: 42 year old male
Reactions: Drug Ineffective, Diarrhoea, Graft Versus Host Disease, Infection
Drug(s) suspected as cause:
Mabcampath
Rapamune
Dosage: 1 df, 1x/day
Enbrel
Dosage: 2 df, 2x/week
Possible Rapamune side effects in 42 year old female
Reported by a physician from Germany on 2012-04-23
Patient: 42 year old female
Reactions: Diarrhoea, Graft Versus Host Disease, Drug Ineffective, Infection
Drug(s) suspected as cause:
Enbrel
Dosage: 2 df, 2x/week
Indication: Product Used FOR Unknown Indication
Rapamune
Dosage: 1 df, 1x/day
Mabcampath
Dosage: unk unk, unk
Possible Rapamune side effects in 42 year old female
Reported by a physician from Germany on 2012-04-13
Patient: 42 year old female
Reactions: Graft Versus Host Disease, Diarrhoea, Drug Ineffective, Infection
Drug(s) suspected as cause:
Rapamune
Dosage: 1 df, 1x/day
Mabcampath
Enbrel
Dosage: 2 df, 2x/week
Possible Rapamune side effects in male
Reported by a consumer/non-health professional from United States on 2012-04-04
Patient: male, weighing 54.4 kg (119.7 pounds)
Reactions: Squamous Cell Carcinoma, Diabetes Mellitus, Nausea, Headache, Tremor, Abdominal Discomfort, Drug Level Above Therapeutic, Diarrhoea, Decreased Appetite, Cardiac Failure Congestive
Drug(s) suspected as cause:
Rapamune
Dosage: 2 mg daily
Administration route: Oral
Indication: Renal Transplant
Start date: 2002-01-01
Prograf
Dosage: 0.5 mg, 2x/day
Indication: Renal Transplant
Start date: 2002-01-01
Prednisone TAB
Dosage: unk
Possible Rapamune side effects in 5 year old male
Reported by a consumer/non-health professional from United States on 2012-03-05
Patient: 5 year old male
Reactions: Diarrhoea, Mouth Ulceration, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Soliris
Indication: Haemolytic Uraemic Syndrome
Rapamune
Possible Rapamune side effects in female
Reported by a consumer/non-health professional from United States on 2012-02-10
Patient: female
Reactions: Aphagia, Diarrhoea, Mouth Ulceration
Drug(s) suspected as cause:
Rapamune
Possible Rapamune side effects in female
Reported by a pharmacist from United States on 2011-10-19
Patient: female
Reactions: Weight Decreased, Diarrhoea, Drug Level Increased, Toxicity To Various Agents
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rapamune
Other drugs received by patient: Mycophenolate Mofetil (Cellcept); Zantac; Diflucan; Vasotec; Magnesium; Trimethoprim; Periactin; Prelone; Folic Acid
|