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Rapamune (Sirolimus) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (17)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Rapamune (Sirolimus) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Rapamune side effects in 55 year old female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: 55 year old female, weighing 90.7 kg (199.5 pounds)

Reactions: Off Label Use, Diarrhoea, Constipation

Drug(s) suspected as cause:
Rapamune



Possible Rapamune side effects in 41 year old male

Reported by a consumer/non-health professional from Brazil on 2012-08-17

Patient: 41 year old male, weighing 71.0 kg (156.2 pounds)

Reactions: Weight Decreased, Diarrhoea, Flatulence, Expired Drug Administered

Drug(s) suspected as cause:
Rapamune

Other drugs received by patient: Ferrous Sulfate; Corus; Prednisone; Angiopril; Myfortic



Possible Rapamune side effects in 11 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-01

Patient: 11 year old female

Reactions: Organising Pneumonia, Post Transplant Lymphoproliferative Disorder, Epstein-Barr Virus Infection, Diarrhoea, Transplant Rejection

Drug(s) suspected as cause:
Rapamune
    Indication: Product Used FOR Unknown Indication

Methylprednisolone
    Indication: Product Used FOR Unknown Indication

Rituximab
    Indication: Post Transplant Lymphoproliferative Disorder

Prednisone
    Indication: Product Used FOR Unknown Indication

Mycophenolate Mofetil
    Indication: Prophylaxis Against Transplant Rejection

Anti-Thymocyte Globulin NOS
    Indication: Product Used FOR Unknown Indication

Tacrolimus
    Indication: Product Used FOR Unknown Indication

Azathioprine
    Indication: Product Used FOR Unknown Indication



Possible Rapamune side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-31

Patient: female, weighing 72.6 kg (159.6 pounds)

Reactions: Drug Ineffective, Mouth Ulceration, Headache, Rash, Tendon Pain, Joint Swelling, Arthralgia, Diarrhoea, Skin Lesion, Oedema Peripheral, Oedema

Drug(s) suspected as cause:
Rapamune
    Dosage: 2 mg, 1x/day
    Administration route: Oral
    Indication: Lymphangioleiomyomatosis
    Start date: 2011-12-08

Tylenol
    Dosage: unk
    Indication: Headache

Other drugs received by patient: Medroxyprogesterone; Doxycycline



Possible Rapamune side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-23

Patient: female, weighing 63.5 kg (139.7 pounds)

Reactions: Vomiting, Diarrhoea, Nausea, Chronic Obstructive Pulmonary Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rapamune

Other drugs received by patient: Metoprolol; Neurontin; Xanax; Simvastatin; Vitamin B-12; Acetylsalicylic Acid



Possible Rapamune side effects in

Reported by a consumer/non-health professional from United States on 2012-05-22

Patient:

Reactions: Drug Ineffective, Graft Versus Host Disease, Diarrhoea, Infection

Drug(s) suspected as cause:
Mabcampath
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Rapamune
    Dosage: 1 df, qd
    Indication: Product Used FOR Unknown Indication

Enbrel
    Dosage: 2 df, 2x/w
    Indication: Product Used FOR Unknown Indication



Possible Rapamune side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-15

Patient: female

Reactions: Diarrhoea, Mouth Ulceration, Oedema, Headache, Rash

Drug(s) suspected as cause:
Rapamune



Possible Rapamune side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: female, weighing 72.6 kg (159.6 pounds)

Reactions: Drug Ineffective, Mouth Ulceration, Rash, Headache, Tendon Pain, Joint Swelling, Diarrhoea, Arthralgia, Skin Lesion, Oedema Peripheral, Oedema

Drug(s) suspected as cause:
Tylenol (Caplet)
    Dosage: unk
    Indication: Headache

Rapamune
    Dosage: 2 mg, daily
    Indication: Lymphangioleiomyomatosis
    Start date: 2011-12-08

Other drugs received by patient: Doxycycline; Medroxyprogesterone



Possible Rapamune side effects in 42 year old male

Reported by a physician from Germany on 2012-05-01

Patient: 42 year old male

Reactions: Diarrhoea, Drug Ineffective, Graft Versus Host Disease, Infection

Drug(s) suspected as cause:
Enbrel
    Dosage: 2 df, 2x/week
    Indication: Product Used FOR Unknown Indication

Mabcampath
    Dosage: unk unk, unk

Rapamune
    Dosage: 1 df, 1x/day



Possible Rapamune side effects in 49 year old male

Reported by a physician from Spain on 2012-04-27

Patient: 49 year old male

Reactions: Diarrhoea, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rapamune

Other drugs received by patient possibly interacting with the suspect drug:
Mycophenolate Mofetil (Cellcept)
    Dosage: 1.25 mg, 1x/day

Prednisolone
    Dosage: 15 mg, 1x/day
    Administration route: Oral
    Indication: Renal Transplant
    Start date: 2009-11-01

Mycophenolate Mofetil (Cellcept)
    Dosage: 2 g, 1x/day
    Administration route: Oral
    Indication: Renal Transplant
    Start date: 2009-11-01

Septra
    Dosage: unk
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2009-11-01

Other drugs received by patient: Omeprazole; Leucovorin Calcium; Cardura



Possible Rapamune side effects in 42 year old male

Reported by a physician from Germany on 2012-04-24

Patient: 42 year old male

Reactions: Drug Ineffective, Diarrhoea, Graft Versus Host Disease, Infection

Drug(s) suspected as cause:
Mabcampath

Rapamune
    Dosage: 1 df, 1x/day

Enbrel
    Dosage: 2 df, 2x/week



Possible Rapamune side effects in 42 year old female

Reported by a physician from Germany on 2012-04-23

Patient: 42 year old female

Reactions: Diarrhoea, Graft Versus Host Disease, Drug Ineffective, Infection

Drug(s) suspected as cause:
Enbrel
    Dosage: 2 df, 2x/week
    Indication: Product Used FOR Unknown Indication

Rapamune
    Dosage: 1 df, 1x/day

Mabcampath
    Dosage: unk unk, unk



Possible Rapamune side effects in 42 year old female

Reported by a physician from Germany on 2012-04-13

Patient: 42 year old female

Reactions: Graft Versus Host Disease, Diarrhoea, Drug Ineffective, Infection

Drug(s) suspected as cause:
Rapamune
    Dosage: 1 df, 1x/day

Mabcampath

Enbrel
    Dosage: 2 df, 2x/week



Possible Rapamune side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-04

Patient: male, weighing 54.4 kg (119.7 pounds)

Reactions: Squamous Cell Carcinoma, Diabetes Mellitus, Nausea, Headache, Tremor, Abdominal Discomfort, Drug Level Above Therapeutic, Diarrhoea, Decreased Appetite, Cardiac Failure Congestive

Drug(s) suspected as cause:
Rapamune
    Dosage: 2 mg daily
    Administration route: Oral
    Indication: Renal Transplant
    Start date: 2002-01-01

Prograf
    Dosage: 0.5 mg, 2x/day
    Indication: Renal Transplant
    Start date: 2002-01-01

Prednisone TAB
    Dosage: unk



Possible Rapamune side effects in 5 year old male

Reported by a consumer/non-health professional from United States on 2012-03-05

Patient: 5 year old male

Reactions: Diarrhoea, Mouth Ulceration, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Soliris
    Indication: Haemolytic Uraemic Syndrome

Rapamune



Possible Rapamune side effects in female

Reported by a consumer/non-health professional from United States on 2012-02-10

Patient: female

Reactions: Aphagia, Diarrhoea, Mouth Ulceration

Drug(s) suspected as cause:
Rapamune



Possible Rapamune side effects in female

Reported by a pharmacist from United States on 2011-10-19

Patient: female

Reactions: Weight Decreased, Diarrhoea, Drug Level Increased, Toxicity To Various Agents

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rapamune

Other drugs received by patient: Mycophenolate Mofetil (Cellcept); Zantac; Diflucan; Vasotec; Magnesium; Trimethoprim; Periactin; Prelone; Folic Acid

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