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Rocephin (Ceftriaxone) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (18)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Rocephin (Ceftriaxone) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Rocephin side effects in female

Reported by a physician from France on 2012-08-15

Patient: female

Reactions: Anaemia, Drug Interaction, Haematoma, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin

Other drugs received by patient possibly interacting with the suspect drug:
Previscan (France)
    Dosage: restarted

Previscan (France)
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2011-01-07

Other drugs received by patient: Escitalopram; Lasix; Depakene; Dicetel; Potassium Chloride



Possible Rocephin side effects in male

Reported by a pharmacist from Japan on 2012-08-08

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: International Normalised Ratio Increased, Haematuria, Drug Interaction, Epistaxis, Pyelonephritis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Miconazole
    Dosage: 2%
    Indication: Laryngitis Fungal
    Start date: 2012-05-10
    End date: 2012-05-19

Rocephin
    Indication: Laryngitis
    Start date: 2012-05-10
    End date: 2012-05-15

Miconazole

Garenoxacin Mesylate
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-15
    End date: 2012-05-21

Rabeprazole Sodium
    Administration route: Oral
    Indication: Prophylaxis Against Gastrointestinal Ulcer
    Start date: 2012-05-11

Selbex
    Administration route: Oral
    Start date: 2012-05-15
    End date: 2012-05-21

Loxonin
    Administration route: Oral
    Start date: 2012-05-15
    End date: 2012-05-21

Selbex
    Administration route: Oral
    Indication: Prophylaxis Against Gastrointestinal Ulcer
    Start date: 2012-05-10
    End date: 2012-05-14

Loxonin
    Administration route: Oral
    Indication: Analgesic Therapy
    Start date: 2012-05-10
    End date: 2012-05-14

Other drugs received by patient possibly interacting with the suspect drug:
Warfarin Sodium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-06-04

Warfarin Sodium
    Administration route: Oral



Possible Rocephin side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient: female, weighing 68.1 kg (149.8 pounds)

Reactions: HIP Arthroplasty, Drug Interaction, Fall, Amnesia, Delusion, Suicidal Ideation, Irritability, Anxiety, Psychotic Disorder, Arthropathy, Pupillary Light Reflex Tests Abnormal, Staphylococcal Infection, Anger, Memory Impairment, Proteus Infection, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin

Other drugs received by patient possibly interacting with the suspect drug:
Vancomycin
    Indication: Arthritis Infective

Pristiq
    Indication: Depression
    Start date: 2012-01-01

Other drugs received by patient: Tramadol HCL; Amitriptline Hydrochloride TAB; Propranolol



Possible Rocephin side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-27

Patient: female, weighing 68.1 kg (149.8 pounds)

Reactions: HIP Arthroplasty, Drug Interaction, Amnesia, Suicidal Ideation, Delusion, Anxiety, Irritability, Psychotic Disorder, Staphylococcal Infection, Anger, Memory Impairment, Proteus Infection, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Indication: Arthritis Infective

Pristiq
    Indication: Depression
    Start date: 2012-01-01

Vancomycin
    Indication: Arthritis Infective

Other drugs received by patient: Tramadol HCL; Propranolol; Amitriptyline Hydrochloride



Possible Rocephin side effects in 67 year old female

Reported by a physician from Switzerland on 2012-07-05

Patient: 67 year old female

Reactions: Fractured Sacrum, Enterocolitis Haemorrhagic, Cytomegalovirus Test Positive, Haemorrhoids, Drug Interaction, Haemorrhagic Anaemia, Diverticulum, Pneumonia Bacterial, Stress Fracture, Lower Gastrointestinal Haemorrhage, Back Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Dosage: 2 g, 1x/day, intravenous
    Indication: Pneumonia Bacterial
    Start date: 2012-03-23
    End date: 2012-04-05

Methotrexate
    Dosage: 1 df, 1x/day, oral
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    Start date: 2005-08-01
    End date: 2012-04-04

Ibuprofen
    Dosage: 1 df per day, oral
    Administration route: Oral
    Indication: Back Disorder
    Start date: 2012-03-01
    End date: 2012-04-04

Prednisone
    Dosage: 10 mg, 1x/day, oral
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    Start date: 2005-08-01

Escitalopram Oxalate
    Dosage: 10 mg, 1x/day,

Fragmin
    Dosage: 5000 iu, 1x/day, subcutaneous
    Indication: Prophylaxis
    Start date: 2012-03-01
    End date: 2012-04-04

Clarithromycin
    Dosage: 500 mg, 2x/day, oral
    Administration route: Oral
    Indication: Pneumonia Bacterial
    Start date: 2012-03-23
    End date: 2012-04-05

Other drugs received by patient: Calcimagon-D3 (Calcium Carbonate, Colecalciferol); Ramipril; Pantoprazole Sodium



Possible Rocephin side effects in male

Reported by a pharmacist from Japan on 2012-07-03

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: International Normalised Ratio Increased, Haematuria, Drug Interaction, Pyelonephritis, Epistaxis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Miconazole
    Dosage: 2%
    Indication: Laryngitis Fungal
    Start date: 2012-05-10
    End date: 2012-05-19

Loxonin
    Administration route: Oral
    Start date: 2012-05-15
    End date: 2012-05-21

Rocephin
    Indication: Laryngitis
    Start date: 2012-05-10
    End date: 2012-05-15

Selbex
    Administration route: Oral
    Indication: Prophylaxis Against Gastrointestinal Ulcer
    Start date: 2012-05-10
    End date: 2012-05-14

Selbex
    Administration route: Oral
    Start date: 2012-05-15
    End date: 2012-05-21

Miconazole

Loxonin
    Administration route: Oral
    Indication: Analgesic Therapy
    Start date: 2012-05-10
    End date: 2012-05-14

Garenoxacin Mesylate
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-15
    End date: 2012-05-21

Rabeprazole Sodium
    Administration route: Oral
    Indication: Prophylaxis Against Gastrointestinal Ulcer
    Start date: 2012-05-11

Other drugs received by patient possibly interacting with the suspect drug:
Warfarin Sodium
    Administration route: Oral

Warfarin Sodium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-06-04



Possible Rocephin side effects in 78 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-25

Patient: 78 year old female, weighing 59.0 kg (129.8 pounds)

Reactions: Clostridium Difficile Colitis, Drug Interaction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rocephin
    Dosage: unk
    Indication: Pneumonia
    Start date: 2009-05-02
    End date: 2009-05-08

Clarithromycin
    Dosage: unk
    Administration route: Oral
    Indication: Helicobacter Infection
    Start date: 2009-05-06
    End date: 2009-05-11

Cefpodoxime Proxetil
    Dosage: unk
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2009-05-09
    End date: 2009-05-11

Amoxicillin
    Dosage: unk
    Administration route: Oral
    Indication: Helicobacter Infection
    Start date: 2009-05-06
    End date: 2009-05-11

Pantoprazole
    Dosage: unk
    Administration route: Oral
    Indication: Helicobacter Infection
    Start date: 2009-04-30

Other drugs received by patient: Digitoxin TAB; Falithrom; Bisoprolol; Quinalapril; Simvastatin; Torsemide; Aldactone; Theophylline



Possible Rocephin side effects in male

Reported by a pharmacist from Japan on 2012-06-14

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: International Normalised Ratio Increased, Haematuria, Drug Interaction, Pyelonephritis, Epistaxis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Loxonin
    Administration route: Oral
    Start date: 2012-05-15
    End date: 2012-05-21

Rocephin
    Indication: Laryngitis
    Start date: 2012-05-10
    End date: 2012-05-15

Miconazole

Miconazole
    Dosage: 2%
    Indication: Laryngitis Fungal
    Start date: 2012-05-10
    End date: 2012-05-19

Loxonin
    Administration route: Oral
    Indication: Analgesic Therapy
    Start date: 2012-05-10
    End date: 2012-05-14

Garenoxacin Mesylate
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-15
    End date: 2012-05-21

Other drugs received by patient possibly interacting with the suspect drug:
Warfarin Sodium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Warfarin Sodium
    Administration route: Oral
    Start date: 2012-06-04

Other drugs received by patient: Selbex; Rabeprazole Sodium; Selbex



Possible Rocephin side effects in female

Reported by a physician from France on 2012-06-05

Patient: female

Reactions: Drug Interaction, Haematoma

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin

Other drugs received by patient possibly interacting with the suspect drug:
Pentoxifylline
    Administration route: Oral
    Indication: Pulmonary Embolism
    End date: 2012-03-08



Possible Rocephin side effects in 66 year old female

Reported by a physician from Switzerland on 2012-05-09

Patient: 66 year old female

Reactions: Blood Alkaline Phosphatase Increased, Liver Injury, Alanine Aminotransferase Increased, Clostridium Difficile Colitis, Drug Interaction, Pancytopenia, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Sepsis, Enterocolitis, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Novalgin (Metamizole Sodium)
    Dosage: 1 g, 1 per 8 hours, iv bolus
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, 1 g, 2/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-03-05

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, 1 g, 2/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-04

Zovirax
    Dosage: 750 mg, 1 per 8 hours, iv bolus
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Esomeprazole Magnesium
    Dosage: 40 mg, 1xday, iv bolus
    Start date: 2012-02-29

Fragmin
    Dosage: 5000 iu, 1x/day, subcutaneous
    Indication: Thrombosis Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Methotrexate Sodium
    Dosage: 5500 mg, during 4 hours, iv drip
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Rocephin
    Dosage: 2 g, 1x/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Other drugs received by patient: Spiricort (Prednisolone); Escitalopram Oxalate; Pantoprazole Sodium; Leucovorin (Folinic Acid)



Possible Rocephin side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-11

Patient: 66 year old female

Reactions: Liver Injury, Drug Level Increased, Sepsis, Drug Interaction, Clostridium Difficile Colitis, Pancytopenia, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Esomeprazole Magnesium
    Dosage: 40mg per day
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-29

Dipyrone TAB
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Methotrexate
    Dosage: 5500mg per day
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Fragmin
    Dosage: 5000u per day
    Indication: Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Zovirax
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Dosage: 2g per day
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Amoxicillin Trihydrate
    Indication: Bacterial Infection
    Start date: 2012-02-29

Other drugs received by patient: Escitalopram; Prednisolone; Carboxypeptidase G2; Pantoprazole; Leucovorin Calcium



Possible Rocephin side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-09

Patient: 66 year old female

Reactions: Liver Injury, Drug Level Increased, Sepsis, Clostridium Difficile Colitis, Drug Interaction, Pancytopenia, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Zovirax
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Fragmin
    Indication: Neoplasm Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Dipyrone TAB
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Other drugs received by patient possibly interacting with the suspect drug:
Esomeprazole Sodium
    Start date: 2012-02-29

Methotrexate
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Amoxicillin Trihydrate
    Indication: Bacterial Infection
    Start date: 2012-02-29

Amoxicillin Trihydrate
    Start date: 2012-03-05

Other drugs received by patient: Pantoprazole; Leucovorin Calcium; Prednisolone; Escitalopram; Carboxypeptidase G2



Possible Rocephin side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-09

Patient: 66 year old female

Reactions: Enterocolitis Bacterial, Liver Injury, Drug Level Increased, Disseminated Intravascular Coagulation, Drug Interaction, Febrile Neutropenia, Clostridium Difficile Colitis, Pancytopenia, Somnolence, Sepsis, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate Sodium
    Dosage: 5500 mg, during 4 hours, iv drip
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-04

Esomeprazole Magnesium
    Dosage: 40 mg, 1x/day, iv bolus
    Start date: 2012-02-29

Zovirax
    Dosage: 750 mg, 1 per 8 hours, iv bolus
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Dosage: 2 g, 1x/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Novalgin (Metamizole Sodium)
    Dosage: 1g, 1 per 8 hours, iv bolus
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Fragmin
    Dosage: 5000 iu, 1x/day, subcutaneous
    Indication: Thrombosis Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Other drugs received by patient: Escitalopram Oxalate; Leucovorin (Folinic Acid); Spiricort (Prednisolone); Pantoprazole Sodium



Possible Rocephin side effects in male

Reported by a physician from France on 2012-03-26

Patient: male

Reactions: Rectal Haemorrhage, International Normalised Ratio Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Dosage: powder form
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-01-28
    End date: 2012-01-30

Previscan
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Lasix; Calcium Carbonate; Avodart; Prednisolone; Triatec 5; Vitamin D; Forlax (France)



Possible Rocephin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-09

Patient: 21 year old male

Reactions: Anticonvulsant Drug Level Decreased, Drug Interaction, Status Epilepticus

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Indication: Ear Infection
    Start date: 2011-09-22
    End date: 2011-09-26

Jantoven
    Indication: Deep Vein Thrombosis
    Start date: 2011-09-01
    End date: 2011-09-25

Dilantin
    Indication: Epilepsy

Other drugs received by patient: Lovenox



Possible Rocephin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-21

Patient: 21 year old male

Reactions: Ear Infection, Anticonvulsant Drug Level Decreased, Drug Interaction, Status Epilepticus

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin

Other drugs received by patient possibly interacting with the suspect drug:
Warfarin Sodium
    Dosage: 2.5 mg, one or two daily
    Administration route: Oral
    Indication: Deep Vein Thrombosis
    Start date: 2011-09-01
    End date: 2011-09-25

Dilantin-125
    Dosage: unk
    Administration route: Oral
    Indication: Epilepsy



Possible Rocephin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-17

Patient: 21 year old male

Reactions: Ear Infection, Drug Interaction, Anticonvulsant Drug Level Decreased, Status Epilepticus

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin

Other drugs received by patient possibly interacting with the suspect drug:
Warfarin Sodium
    Dosage: 2.5 mg, one or two daily
    Administration route: Oral
    Indication: Deep Vein Thrombosis
    Start date: 2011-09-01
    End date: 2011-09-25

Dilantin-125
    Dosage: unk
    Administration route: Oral
    Indication: Epilepsy



Possible Rocephin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-13

Patient: 21 year old male

Reactions: Drug Interaction, Ear Infection, Status Epilepticus, Anticonvulsant Drug Level Below Therapeutic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Dosage: parenteral
    Indication: Ear Infection
    Start date: 2011-09-22
    End date: 2011-09-26

Jantoven
    Dosage: 2.5 mg, qd-bid, oral
    Administration route: Oral
    Indication: Deep Vein Thrombosis
    Start date: 2011-09-01
    End date: 2011-09-25

Dilantin
    Dosage: oral
    Administration route: Oral
    Indication: Epilepsy

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