This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Selegiline and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (28)
Reports by Reaction Type
Hallucination, Visual (10),
Pneumonia Aspiration (9),
Intentional Overdose (9),
Coma (9),
Respiratory Failure (8),
Convulsion (6),
Confusional State (5),
Dopamine Dysregulation Syndrome (5),
ON and Off Phenomenon (5),
Myoclonus (5),
Suicide Attempt (5),
Hypomania (4)
Possible Selegiline side effects in 65 year old female
Reported by a pharmacist from United States on 2012-07-30
Patient: 65 year old female, weighing 62.5 kg (137.5 pounds)
Reactions: Extrapyramidal Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Other drugs received by patient: Diazepam; Aspirin; Amantadine HCL; Ropinorole; Dulcolax; Hydrocodone Bitartrate and Acetaminophen; Carbidopa and Levodopa
Possible Selegiline side effects in 62 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-10
Patient: 62 year old female
Reactions: Pathological Gambling, Condition Aggravated
Drug(s) suspected as cause:
Pramipexole Dihychloride
Dosage: 2.1 mg/day
Indication: Parkinson's Disease
Selegiline
Dosage: 10 mg/day
Indication: Parkinson's Disease
Sertraline Hydrochloride
Dosage: 50 mg/ day
Indication: Pathological Gambling
Possible Selegiline side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-03
Patient:
Reactions: Syncope, Drug Interaction, Dizziness
Drug(s) suspected as cause:
Selegiline
Methylphenidate
Clomipramine HCL
Possible Selegiline side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-03
Patient:
Reactions: Syncope, Dizziness, Drug Interaction
Drug(s) suspected as cause:
Clomipramine HCL
Selegiline
Methylphenidate
Possible Selegiline side effects in
Reported by a physician from United States on 2012-07-02
Patient:
Reactions: Dopamine Dysregulation Syndrome, Drug Interaction, Gambling
Drug(s) suspected as cause:
Pramipexole Dihychloride
Levodopa
Selegiline
Dosage: 10 mg
Possible Selegiline side effects in 55 year old male
Reported by a physician from Finland on 2012-06-26
Patient: 55 year old male
Reactions: Therapeutic Response Unexpected, Impulsive Behaviour
Drug(s) suspected as cause:
Carbidopa + Levodopa
Dosage: 100/25-200/50 mg, daily
Indication: Parkinson's Disease
Start date: 2004-01-01
Cabergoline
Dosage: 1-2 mg, daily
Indication: Parkinson's Disease
Start date: 2002-01-01
Selegiline
Dosage: 5 mg, daily
Indication: Parkinson's Disease
Start date: 2001-01-01
Possible Selegiline side effects in 62 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-25
Patient: 62 year old female
Reactions: Pathological Gambling, Condition Aggravated
Drug(s) suspected as cause:
Pramipexole Dihychlloride
Dosage: 2.1 mg/day
Indication: Parkinson's Disease
Sertraline Hydrochloride
Dosage: unk
Indication: Pathological Gambling
Selegiline
Indication: Parkinson's Disease
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-27
Patient: 50 year old male
Reactions: Confusional State, Pneumonia Aspiration, Intentional Overdose, Coma, Convulsion, Myoclonus, Hallucination, Visual, Suicide Attempt
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Trazodone HCL
Nitrazepam
Carbamazepine
Selegiline
Dosage: 10 mg/daily
Indication: Depression
Valproate Sodium
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-24
Patient: 50 year old male
Reactions: Pneumonia Aspiration, Intentional Overdose, Coma, Serotonin Syndrome, Convulsion, Hallucination, Visual, Respiratory Failure, Multiple Drug Overdose Intentional
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Indication: Intentional Overdose
Start date: 2010-11-01
Carbamazepine
Indication: Intentional Overdose
Start date: 2010-11-01
Trazodone HCL
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Nitrazepam
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Indication: Depression
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Valproic Acid
Indication: Intentional Overdose
Start date: 2010-11-01
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-24
Patient: 50 year old male
Reactions: Pneumonia Aspiration, Intentional Overdose, Respiratory Failure, Hallucination, Visual, Coma, Serotonin Syndrome, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Start date: 2005-05-01
Carbamazepine
Indication: Intentional Overdose
Start date: 2010-11-01
Nitrazepam
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Selegiline
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Indication: Depression
Start date: 2010-11-01
Valproic Acid
Indication: Intentional Overdose
Start date: 2010-11-01
Trazodone HCL
Indication: Intentional Overdose
Start date: 2010-11-01
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-24
Patient: 50 year old male
Reactions: Pneumonia Aspiration, Intentional Overdose, Respiratory Failure, Hallucination, Visual, Coma, Serotonin Syndrome, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Start date: 2005-05-01
Selegiline
Indication: Depression
Start date: 2010-11-01
Nitrazepam
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Carbamazepine
Indication: Intentional Overdose
Start date: 2010-11-01
Trazodone HCL
Indication: Intentional Overdose
Start date: 2010-11-01
Valproic Acid
Indication: Intentional Overdose
Start date: 2010-11-01
Possible Selegiline side effects in 45 year old male
Reported by a individual with unspecified qualification from Finland on 2012-01-24
Patient: 45 year old male
Reactions: Anxiety, ON and Off Phenomenon, Apathy, Dopamine Dysregulation Syndrome, Overdose, Hypersexuality, Hypomania
Drug(s) suspected as cause:
Carbidopa + Levodopa
Dosage: 400/100 mg daily
Pramipexole Dihychlloride
Dosage: 2.1 mg, daily
Selegiline
Dosage: 5 mg, daily
Amantadine HCL
Dosage: 100 mg, daily
Pramipexole Dihychlloride
Dosage: 2.8 mg, daily
Biperiden Hydrochloride TAB
Dosage: 4 mg, daily
Carbidopa + Levodopa
Dosage: 600/150/800 mg daily
Propranolol
Dosage: 160 mg, daily
Carbidopa + Levodopa
Dosage: 600/150/800 mg daily
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-24
Patient: 50 year old male
Reactions: Pneumonia Aspiration, Respiratory Failure, Intentional Overdose, Hallucination, Visual, Coma, Serotonin Syndrome, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carbamazepine
Indication: Intentional Overdose
Start date: 2010-11-01
Nitrazepam
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Indication: Depression
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Trazodone HCL
Indication: Intentional Overdose
Start date: 2010-11-01
Selegiline
Start date: 2005-05-01
Valproic Acid
Indication: Intentional Overdose
Start date: 2010-11-01
Possible Selegiline side effects in 45 year old male
Reported by a health professional (non-physician/pharmacist) from Finland on 2012-01-23
Patient: 45 year old male
Reactions: Apathy, Dopamine Dysregulation Syndrome, ON and Off Phenomenon, Anxiety, Hypersexuality, Hypomania
Drug(s) suspected as cause:
Selegiline
Dosage: 5 mg, daily
Pramipexole Dihychlloride
Dosage: 2.1 mg, daily
Amantadine HCL
Dosage: 100 mg, daily
Pramipexole Dihychlloride
Dosage: 2.8 mg, daily
Entacapone-Levodopa-Carbidopa
Dosage: 400/100 mg daily
Propranolol
Dosage: 160 mg, daily
Entacapone-Levodopa-Carbidopa
Dosage: 600/150/800 mg daily
Biperiden Hydrochloride TAB
Dosage: 4 mg, daily
Possible Selegiline side effects in male
Reported by a health professional (non-physician/pharmacist) from Spain on 2012-01-12
Patient: male
Reactions: Apathy, Polydipsia, Dopamine Dysregulation Syndrome, Hypersexuality, Intentional Drug Misuse, Hypomania
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Dosage: 5 mg
Indication: Parkinson's Disease
Amantadine HCL
Dosage: 100 mg
Indication: Parkinson's Disease
Biperiden Hydrochloride TAB
Dosage: 4 mg
Indication: Parkinson's Disease
Pramipexole Dihychlloride
Dosage: 2.1 mg
Carbidopa + Levodopa
Dosage: levodopa/carbidopa 400/100 mg
Indication: Parkinson's Disease
Pramipexole Dihychlloride
Dosage: 4.2 mg
Pramipexole Dihychlloride
Dosage: 2.8 mg
Indication: Parkinson's Disease
Possible Selegiline side effects in male
Reported by a physician from United States on 2012-01-04
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Pulse Abnormal, Syncope, Atrial Flutter, Heart Rate Increased, Gait Disturbance
Drug(s) suspected as cause:
Selegiline
Other drugs received by patient: Eldepryl
Possible Selegiline side effects in 69 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-28
Patient: 69 year old female
Reactions: Gastrointestinal Hypomotility, Infrequent Bowel Movements
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Dosage: 5 mg, daily
Indication: Parkinson's Disease
Entacapone
Dosage: 300 mg, daily
Indication: Parkinson's Disease
Levodopa
Dosage: 900 mg, daily
Indication: Parkinson's Disease
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-16
Patient: 50 year old male
Reactions: Overdose, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Indication: Depression
Start date: 2005-05-01
Valproate Sodium
Indication: Product Used FOR Unknown Indication
Carbamazepine
Indication: Product Used FOR Unknown Indication
Trazodone HCL
Indication: Product Used FOR Unknown Indication
Nitrazepam
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Hypnotics; Mood Stablizers
Possible Selegiline side effects in male
Reported by a health professional (non-physician/pharmacist) from Spain on 2011-12-15
Patient: male
Reactions: Dopamine Dysregulation Syndrome, Polydipsia, Apathy, Hypersexuality, Intentional Drug Misuse, Hypomania
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Pramipexole Dihydrochloride
Dosage: 4.2 mg
Selegiline
Dosage: 5 mg
Indication: Parkinson's Disease
Carbidopa + Levodopa
Dosage: levodopa/carbidopa 400/100 mg
Indication: Parkinson's Disease
Amantadine HCL
Dosage: 100 mg
Indication: Parkinson's Disease
Biperiden Hydrochloride TAB
Dosage: 4 mg
Indication: Parkinson's Disease
Pramipexole Dihydrochloride
Dosage: 2.8 mg
Indication: Parkinson's Disease
Pramipexole Dihydrochloride
Dosage: 2.1 mg
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-15
Patient: 50 year old male
Reactions: Confusional State, Pneumonia Aspiration, Intentional Overdose, Coma, Hyperhidrosis, Myoclonus, Grand MAL Convulsion, Hallucination, Visual, Respiratory Failure, Suicide Attempt, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Trazodone HCL
Dosage: 2250 mg, unk
Start date: 2010-11-01
Nitrazepam
Dosage: 70 mg, unk
Start date: 2010-11-01
Trazodone HCL
Dosage: unk
Carbamazepine
Dosage: 8600 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 195 mg, unk
Start date: 2010-11-01
Valproate Sodium
Dosage: 16000 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 10 mg, daily
Indication: Depression
Start date: 2005-05-01
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-15
Patient: 50 year old male
Reactions: Confusional State, Pneumonia Aspiration, Intentional Overdose, Coma, Hyperhidrosis, Grand MAL Convulsion, Myoclonus, Hallucination, Visual, Respiratory Failure, Suicide Attempt, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Dosage: 10 mg, daily
Indication: Depression
Start date: 2005-05-01
Trazodone HCL
Dosage: 2250 mg, unk
Start date: 2010-11-01
Valproate Sodium
Dosage: 16000 mg, unk
Start date: 2010-11-01
Nitrazepam
Dosage: 70 mg, unk
Start date: 2010-11-01
Carbamazepine
Dosage: 8600 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 195 mg, unk
Start date: 2010-11-01
Trazodone HCL
Dosage: unk
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-09
Patient: 50 year old male
Reactions: Confusional State, Pneumonia Aspiration, Intentional Overdose, Coma, Hyperhidrosis, Grand MAL Convulsion, Myoclonus, Hallucination, Visual, Respiratory Failure, Suicide Attempt, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Dosage: 10 mg, daily
Indication: Depression
Start date: 2005-05-01
Trazodone HCL
Dosage: unk
Carbamazepine
Dosage: 8600 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 195 mg, unk
Start date: 2010-11-01
Trazodone HCL
Dosage: 2250 mg, unk
Start date: 2010-11-01
Valproate Sodium
Dosage: 16000 mg, unk
Start date: 2010-11-01
Nitrazepam
Dosage: 70 mg, unk
Start date: 2010-11-01
Possible Selegiline side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-09
Patient: 50 year old male
Reactions: Confusional State, Pneumonia Aspiration, Intentional Overdose, Coma, Hyperhidrosis, Myoclonus, Grand MAL Convulsion, Hallucination, Visual, Respiratory Failure, Suicide Attempt, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Trazodone HCL
Dosage: 2250 mg, unk
Start date: 2010-11-01
Nitrazepam
Dosage: 70 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 10 mg, daily
Indication: Depression
Start date: 2005-05-01
Carbamazepine
Dosage: 8600 mg, unk
Start date: 2010-11-01
Selegiline
Dosage: 195 mg, unk
Start date: 2010-11-01
Trazodone HCL
Dosage: unk
Valproate Sodium
Dosage: 16000 mg, unk
Start date: 2010-11-01
Possible Selegiline side effects in 56 year old male
Reported by a physician from Germany on 2011-11-09
Patient: 56 year old male
Reactions: ON and Off Phenomenon, Sleep Disorder, Paraesthesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Levopar
Dosage: 125 mg 3 x 1 tablet
Selegiline
Dosage: 5 mg
Other drugs received by patient: Victoza; Metformin Hydrochloride; Ramipril; Ezedrol; Metformin HCL; Lantus; Hydrochlorothiazide; Amlodipine; Aspirin; Metformin Hydrochloride
Possible Selegiline side effects in 56 year old male
Reported by a physician from Germany on 2011-11-08
Patient: 56 year old male
Reactions: ON and Off Phenomenon, Sleep Disorder, Paraesthesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Selegiline
Dosage: 5 mg
Levopar
Dosage: 125 mg 3 x 1 tablet
Neupro
Other drugs received by patient: Aspirin; Ezedrol; Amlodipine; Metformin Hydrochloride; Metfformin Hydrochloride; Victoza; Hydrochlorothiazide; Lantus; Metformin Hydrochloride; Ramipril
Possible Selegiline side effects in 56 year old male
Reported by a physician from Germany on 2011-11-01
Patient: 56 year old male
Reactions: ON and Off Phenomenon, Sleep Disorder, Hallucination, Visual, Paraesthesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Levopar
Dosage: 125 mg 3 x 1 tablet
Selegiline
Dosage: 5 mg
Neupro
Indication: Parkinson's Disease
Other drugs received by patient: Metformin Hydrochloride; Victoza; Amlodipine; Lantus; Ramipril; Hydrochlorothiazide; Aspirin; Ezedrol; Metformin HCL; Metformin Hydrochloride
Possible Selegiline side effects in 34 year old male
Reported by a health professional (non-physician/pharmacist) from Brazil on 2011-10-14
Patient: 34 year old male
Reactions: Weight Increased, Middle Insomnia, Rapid Eye Movements Sleep Abnormal, Sleep Apnoea Syndrome, Binge Eating, Somnolence, Sleep-Related Eating Disorder
Drug(s) suspected as cause:
Amantadine HCL
Dosage: 300 mg
Indication: Parkinson's Disease
Selegiline
Dosage: 10 mg
Indication: Parkinson's Disease
Pramipexole Dihydrochloride
Dosage: 4.5 mg
Indication: Parkinson's Disease
Biperiden Hydrochloride TAB
Dosage: 6 mg
Indication: Parkinson's Disease
Possible Selegiline side effects in male
Reported by a physician from China on 2011-10-04
Patient: male, weighing 69.0 kg (151.8 pounds)
Reactions: Humerus Fracture, Joint Dislocation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ropinirole
Dosage: 2mg per day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2010-09-28
Selegiline
Dosage: 5mg per day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2011-02-01
Other drugs received by patient: Celecoxib; Madopar
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