Index of reports
> Cases with Niemann-Pick Disease (14)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zavesca (Miglustat) where reactions include niemann-pick disease. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Zavesca side effects in 31 year old female
Reported by a physician from Switzerland on 2012-08-17
Patient: 31 year old female, weighing 53.0 kg (116.6 pounds)
Reactions: Weight Decreased, Dysphagia, Pneumonia Aspiration, Disease Progression, Tremor, Diarrhoea, Niemann-Pick Disease, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Zavesca
Other drugs received by patient: Nozinan; Diazepam; Amitriptyline HCL
Possible Zavesca side effects in 7 year old female
Reported by a physician from Netherlands on 2012-08-03
Patient: 7 year old female
Reactions: Respiratory Failure, Niemann-Pick Disease
Adverse event resulted in: death
Drug(s) suspected as cause:
Zavesca
Possible Zavesca side effects in female
Reported by a physician from Switzerland on 2012-07-27
Patient: female, weighing 53.0 kg (116.6 pounds)
Reactions: Weight Decreased, Dysphagia, Tremor, Disease Progression, Death, Diarrhoea, Niemann-Pick Disease, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Zavesca
Other drugs received by patient: Nozinan; Amitriptyline HCL; Diazepam
Possible Zavesca side effects in male
Reported by a consumer/non-health professional from Australia on 2012-07-27
Patient: male
Reactions: Dysphagia, Ataxia, Palliative Care, Niemann-Pick Disease, Disease Progression
Adverse event resulted in: death, disablity
Drug(s) suspected as cause:
Zavesca
Possible Zavesca side effects in 5 year old female
Reported by a physician from France on 2012-07-03
Patient: 5 year old female
Reactions: Gastrointestinal Disorder, NO Therapeutic Response, Condition Aggravated, Niemann-Pick Disease
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zavesca
Dosage: 150 mg, qd
Administration route: Oral
Indication: Niemann-Pick Disease
Start date: 2010-04-01
Zavesca
Dosage: 50 mg, qd
Administration route: Oral
Possible Zavesca side effects in female
Reported by a physician from France on 2012-05-23
Patient: female
Reactions: Dysphagia, Wheelchair User, Drug Ineffective, Dementia, Condition Aggravated, Cognitive Disorder, Tremor, Dysarthria, Gait Disturbance, Niemann-Pick Disease
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Zavesca
Dosage: 200 mg, tid
Administration route: Oral
Start date: 2010-03-25
Zavesca
Dosage: 100 mg, tid
Administration route: Oral
Indication: Niemann-Pick Disease
End date: 2011-05-09
Possible Zavesca side effects in 9 year old male
Reported by a physician from Spain on 2012-03-28
Patient: 9 year old male
Reactions: Condition Aggravated, Niemann-Pick Disease
Adverse event resulted in: death
Drug(s) suspected as cause:
Zavesca
Possible Zavesca side effects in male
Reported by a physician from Germany on 2012-02-22
Patient: male
Reactions: Gastrostomy Tube Insertion, Pain, Musculoskeletal Stiffness, Salivary Hypersecretion, Hypertonia, Niemann-Pick Disease, Disease Progression
Drug(s) suspected as cause:
Zavesca
Dosage: 75 mg, bid
Administration route: Oral
Indication: Niemann-Pick Disease
Start date: 2009-05-01
End date: 2011-12-07
Zavesca
Dosage: 50 mg, bid
Administration route: Oral
Start date: 2009-03-01
End date: 2009-05-01
Other drugs received by patient: Hydrochlorothiazide; Spironolactone; Urso Falk; Singulair; Kanavit
Possible Zavesca side effects in 6 year old female
Reported by a physician from United States on 2012-01-27
Patient: 6 year old female
Reactions: Stereotypy, Condition Aggravated, Visual Acuity Reduced, Ataxia, Cognitive Disorder, Speech Disorder, Anxiety, Psychomotor Skills Impaired, Eye Movement Disorder, Memory Impairment, Niemann-Pick Disease
Drug(s) suspected as cause:
Zavesca
Other drugs received by patient: Acetylcysteine
Possible Zavesca side effects in 6 year old female
Reported by a physician from United States on 2012-01-27
Patient: 6 year old female
Reactions: Stereotypy, Condition Aggravated, Ataxia, Visual Acuity Reduced, Cognitive Disorder, Speech Disorder, Anxiety, Psychomotor Skills Impaired, Eye Movement Disorder, Memory Impairment, Niemann-Pick Disease
Drug(s) suspected as cause:
Zavesca
Other drugs received by patient: Acetylcysteine
Possible Zavesca side effects in male
Reported by a physician from Germany on 2012-01-13
Patient: male
Reactions: Gastrostomy Tube Insertion, Pain, Musculoskeletal Stiffness, Salivary Hypersecretion, Disease Progression, Hypertonia, Niemann-Pick Disease
Drug(s) suspected as cause:
Zavesca
Possible Zavesca side effects in male
Reported by a physician from Germany on 2012-01-04
Patient: male
Reactions: Gastrostomy Tube Insertion, Pain, Musculoskeletal Stiffness, Condition Aggravated, Salivary Hypersecretion, Hypertonia, Niemann-Pick Disease
Drug(s) suspected as cause:
Zavesca
Possible Zavesca side effects in female
Reported by a physician from France on 2011-12-13
Patient: female, weighing 47.0 kg (103.4 pounds)
Reactions: Mental Impairment, Weight Decreased, Dysphagia, Condition Aggravated, Appetite Disorder, Niemann-Pick Disease
Drug(s) suspected as cause:
Zavesca
Dosage: unk mg, unk
Administration route: Oral
Indication: Niemann-Pick Disease
Start date: 2010-05-01
End date: 2011-10-01
Zavesca
Dosage: unk mg, unk
Administration route: Oral
Start date: 2011-11-10
Possible Zavesca side effects in 2 year old male
Reported by a physician from United Kingdom on 2011-11-01
Patient: 2 year old male, weighing 7.8 kg (17.2 pounds)
Reactions: Niemann-Pick Disease, Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Zavesca
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