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Zovirax (Acyclovir) - Pancytopenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pancytopenia (10)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zovirax (Acyclovir) where reactions include pancytopenia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Zovirax side effects in 55 year old

Reported by a physician from Japan on 2012-05-31

Patient: 55 year old

Reactions: Pneumonia, Gastric Ulcer Haemorrhage, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neoral
    Dosage: 75-175 mg
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-01-22
    End date: 2001-03-05

Allopurinol
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-02-14
    End date: 2001-02-21

Cellcept
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2001-01-23
    End date: 2001-01-26

Prograf
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-03-05

Cotrim
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-02-01
    End date: 2001-02-21

Cellcept
    Dosage: dosage is uncertain.
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-01-23
    End date: 2001-01-23

Omeprazole
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-02-08
    End date: 2001-02-27

Enalapril Maleate
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-02-15
    End date: 2001-02-28

Cellcept
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2001-01-27
    End date: 2001-01-27

Zovirax
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-01-22
    End date: 2001-02-21

Cellcept
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2001-01-31
    End date: 2001-01-31

Cellcept
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2001-02-01
    End date: 2001-02-18

Diflucan
    Administration route: Oral
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2001-01-22
    End date: 2001-02-21

Other drugs received by patient: Akineton; Lasix; Aldactone; Haloperidol; Haloperidol



Possible Zovirax side effects in 66 year old female

Reported by a physician from Switzerland on 2012-05-09

Patient: 66 year old female

Reactions: Blood Alkaline Phosphatase Increased, Liver Injury, Alanine Aminotransferase Increased, Clostridium Difficile Colitis, Drug Interaction, Pancytopenia, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Sepsis, Enterocolitis, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Novalgin (Metamizole Sodium)
    Dosage: 1 g, 1 per 8 hours, iv bolus
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, 1 g, 2/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-03-05

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, 1 g, 2/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-04

Zovirax
    Dosage: 750 mg, 1 per 8 hours, iv bolus
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Esomeprazole Magnesium
    Dosage: 40 mg, 1xday, iv bolus
    Start date: 2012-02-29

Fragmin
    Dosage: 5000 iu, 1x/day, subcutaneous
    Indication: Thrombosis Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Methotrexate Sodium
    Dosage: 5500 mg, during 4 hours, iv drip
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Rocephin
    Dosage: 2 g, 1x/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Other drugs received by patient: Spiricort (Prednisolone); Escitalopram Oxalate; Pantoprazole Sodium; Leucovorin (Folinic Acid)



Possible Zovirax side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-11

Patient: 66 year old female

Reactions: Liver Injury, Drug Level Increased, Sepsis, Drug Interaction, Clostridium Difficile Colitis, Pancytopenia, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Esomeprazole Magnesium
    Dosage: 40mg per day
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-29

Dipyrone TAB
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Methotrexate
    Dosage: 5500mg per day
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Fragmin
    Dosage: 5000u per day
    Indication: Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Zovirax
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Dosage: 2g per day
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Amoxicillin Trihydrate
    Indication: Bacterial Infection
    Start date: 2012-02-29

Other drugs received by patient: Escitalopram; Prednisolone; Carboxypeptidase G2; Pantoprazole; Leucovorin Calcium



Possible Zovirax side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-09

Patient: 66 year old female

Reactions: Enterocolitis Bacterial, Liver Injury, Drug Level Increased, Disseminated Intravascular Coagulation, Drug Interaction, Febrile Neutropenia, Clostridium Difficile Colitis, Pancytopenia, Somnolence, Sepsis, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate Sodium
    Dosage: 5500 mg, during 4 hours, iv drip
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Amoxicillin Trihydrate
    Dosage: 2 g, 1 per 4 hours, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-04

Esomeprazole Magnesium
    Dosage: 40 mg, 1x/day, iv bolus
    Start date: 2012-02-29

Zovirax
    Dosage: 750 mg, 1 per 8 hours, iv bolus
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Dosage: 2 g, 1x/day, iv bolus
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Novalgin (Metamizole Sodium)
    Dosage: 1g, 1 per 8 hours, iv bolus
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Fragmin
    Dosage: 5000 iu, 1x/day, subcutaneous
    Indication: Thrombosis Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Other drugs received by patient: Escitalopram Oxalate; Leucovorin (Folinic Acid); Spiricort (Prednisolone); Pantoprazole Sodium



Possible Zovirax side effects in 66 year old female

Reported by a physician from Switzerland on 2012-04-09

Patient: 66 year old female

Reactions: Liver Injury, Drug Level Increased, Sepsis, Clostridium Difficile Colitis, Drug Interaction, Pancytopenia, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Zovirax
    Indication: Encephalitis Viral
    Start date: 2012-02-29
    End date: 2012-03-04

Fragmin
    Indication: Neoplasm Prophylaxis
    Start date: 2012-02-29
    End date: 2012-03-04

Rocephin
    Indication: Bacterial Infection
    Start date: 2012-02-29
    End date: 2012-03-03

Dipyrone TAB
    Indication: Pyrexia
    Start date: 2012-02-29
    End date: 2012-03-03

Other drugs received by patient possibly interacting with the suspect drug:
Esomeprazole Sodium
    Start date: 2012-02-29

Methotrexate
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-03-03
    End date: 2012-03-03

Amoxicillin Trihydrate
    Indication: Bacterial Infection
    Start date: 2012-02-29

Amoxicillin Trihydrate
    Start date: 2012-03-05

Other drugs received by patient: Pantoprazole; Leucovorin Calcium; Prednisolone; Escitalopram; Carboxypeptidase G2



Possible Zovirax side effects in 18 year old male

Reported by a pharmacist from Austria on 2012-04-03

Patient: 18 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Personality Change, Immune Reconstitution Syndrome, Encephalitis, Pyrexia, Impulsive Behaviour, Device Related Infection, Suicidal Ideation, Herpes Zoster, C-Reactive Protein Increased, Circulatory Collapse, Mood Swings, Dysphagia, Lymphopenia, General Physical Health Deterioration, Pancytopenia, Muscle Twitching, Epilepsy, Tremor, Dysarthria, Hypophagia, Vertigo

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Zovirax
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-01-11
    End date: 2011-01-27

Zovirax
    Dosage: 800mg three times per day
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2010-07-18
    End date: 2010-12-26

Zovirax
    Dosage: 750mg three times per day
    Administration route: Oral
    Start date: 2010-12-30
    End date: 2011-01-05

Zovirax
    Dosage: 600mg three times per day
    Administration route: Oral
    Start date: 2011-01-08
    End date: 2011-01-11

Other drugs received by patient: Ganciclovir



Possible Zovirax side effects in 18 year old male

Reported by a pharmacist from Austria on 2012-03-19

Patient: 18 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Personality Change, Immune Reconstitution Syndrome, Encephalitis, Impulsive Behaviour, Pyrexia, Device Related Infection, Suicidal Ideation, Herpes Zoster, C-Reactive Protein Increased, Circulatory Collapse, Mood Swings, Dysphagia, Lymphopenia, Pancytopenia, General Physical Health Deterioration, Muscle Twitching, Epilepsy, Tremor, Dysarthria, Hypophagia, Vertigo

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Zovirax
    Dosage: 800mg three times per day
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2010-07-18
    End date: 2010-12-26

Zovirax
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-01-11
    End date: 2011-01-27

Zovirax
    Dosage: 600mg three times per day
    Administration route: Oral
    Start date: 2011-01-08
    End date: 2011-01-11

Zovirax
    Dosage: 750mg three times per day
    Administration route: Oral
    Start date: 2010-12-30
    End date: 2011-01-05

Other drugs received by patient: Ganciclovir



Possible Zovirax side effects in 18 year old male

Reported by a physician from Austria on 2012-02-27

Patient: 18 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Personality Change, Immune Reconstitution Syndrome, Encephalitis, Pyrexia, Device Related Infection, Impulsive Behaviour, Suicidal Ideation, Herpes Zoster, C-Reactive Protein Increased, Circulatory Collapse, Mood Swings, Dysphagia, Lymphopenia, General Physical Health Deterioration, Pancytopenia, Epilepsy, Muscle Twitching, Tremor, Dysarthria, Hypophagia, Vertigo

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Zovirax
    Dosage: 800mg three times per day
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2010-06-18
    End date: 2010-12-26

Zovirax
    Administration route: Oral
    Start date: 2011-01-11
    End date: 2011-01-27

Zovirax
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-12-31
    End date: 2010-12-31

Other drugs received by patient: Ganciclovir



Possible Zovirax side effects in 18 year old male

Reported by a physician from Austria on 2012-02-15

Patient: 18 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Personality Change, Immune Reconstitution Syndrome, Encephalitis, Pyrexia, Device Related Infection, Impulsive Behaviour, Herpes Zoster, Suicidal Ideation, C-Reactive Protein Increased, Circulatory Collapse, Mood Swings, Dysphagia, Lymphopenia, General Physical Health Deterioration, Pancytopenia, Muscle Twitching, Epilepsy, Tremor, Dysarthria, Hypophagia, Vertigo

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Zovirax



Possible Zovirax side effects in female

Reported by a physician from France on 2011-12-02

Patient: female

Reactions: Pancytopenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zovirax

Other drugs received by patient: Urbanyl; Rebif; Keppra; Alprazolam; Imovane; Solu-Medrol

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