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Zyvox (Linezolid) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (31)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zyvox (Linezolid) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 31   Next >>

Possible Zyvox side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-27

Patient: 65 year old female, weighing 64.0 kg (140.8 pounds)

Reactions: Drug Interaction, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: unk
    Start date: 2008-10-25
    End date: 2009-01-27

Amiodarone HCL
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Zyvox
    Dosage: 600 mg, bid
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Other drugs received by patient possibly interacting with the suspect drug:
Torsemide
    Dosage: 10 mg, bid
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29

Spironolactone
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Xipamide
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Other drugs received by patient: Acetaminophen; Enoxaparin Sodium; Simvastatin; Amitriptyline HCL; Novalgin; Omeprazole; Oxycodone HCL; Metoprolol Tartrate; Digitoxin TAB



Possible Zyvox side effects in 15 year old male

Reported by a physician from United States on 2012-08-17

Patient: 15 year old male, weighing 47.0 kg (103.4 pounds)

Reactions: Blood Bilirubin Increased, Agitation, Insomnia, Drug Interaction, Faeces Discoloured

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Sinemet
    Dosage: unk
    Indication: Quadriplegia
    End date: 2012-07-01

Sinemet
    Dosage: unk
    Start date: 2012-07-01

Other drugs received by patient: Vancomycin; Baclofen; Tylenol; Albuterol



Possible Zyvox side effects in male

Reported by a pharmacist from United States on 2012-08-02

Patient: male, weighing 47.0 kg (103.4 pounds)

Reactions: Agitation, Blood Bilirubin Increased, Insomnia, Drug Interaction, Faeces Discoloured

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Sinemet
    Dosage: unk
    Indication: Quadriplegia
    End date: 2012-07-01

Sinemet
    Dosage: unk
    Start date: 2012-07-01

Other drugs received by patient: Vancomycin; Baclofen; Tylenol (Caplet); Albuterol



Possible Zyvox side effects in male

Reported by a pharmacist from United States on 2012-07-27

Patient: male, weighing 47.0 kg (103.4 pounds)

Reactions: Agitation, Insomnia, Drug Interaction, Faeces Discoloured

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Sinemet
    Dosage: unk
    Indication: Quadriplegia
    End date: 2012-07-01

Sinemet
    Dosage: unk
    Start date: 2012-07-01

Other drugs received by patient: Albuterol; Tylenol; Baclofen; Vancomycin



Possible Zyvox side effects in 91 year old female

Reported by a physician from United States on 2012-07-25

Patient: 91 year old female

Reactions: Abdominal Discomfort, Haematochezia, Staphylococcal Infection, Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Xarelto
    Dosage: 15 mg, unk
    Administration route: Oral
    Indication: Atrial Fibrillation



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2012-06-28

Patient: female, weighing 91.4 kg (201.1 pounds)

Reactions: Drug Interaction, Coagulation Time Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Argatroban
    Dosage: 2 mcg/kg/min, frequency: with frequent titration
    Indication: Heparin-Induced Thrombocytopenia
    Start date: 2007-03-25
    End date: 2007-03-31

Zyvox
    Dosage: frequency: bid q12 hrs
    Indication: Urinary Tract Infection
    Start date: 2007-03-27

Other drugs received by patient: Fragmin; Famotidine; Methylpednisolone Sodium Succinate; Warfarin Sodium



Possible Zyvox side effects in 51 year old male

Reported by a pharmacist from Spain on 2012-06-28

Patient: 51 year old male

Reactions: Mania, Drug Interaction, Serotonin Syndrome

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Fluvoxamine Maleate
    Dosage: 100 mg, 3x/day
    Administration route: Oral
    Indication: Depression
    Start date: 2010-11-26
    End date: 2012-05-12

Other drugs received by patient: Clozapine; Topamax; Tramadol



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2012-06-22

Patient: female, weighing 91.4 kg (201.1 pounds)

Reactions: Drug Interaction, Coagulation Time Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Argatroban
    Dosage: 2 mcg/kg/min, frequency: with frequent titration
    Indication: Heparin-Induced Thrombocytopenia
    Start date: 2007-03-25
    End date: 2007-03-31

Zyvox
    Dosage: frequency: bid q12 hrs
    Indication: Urinary Tract Infection
    Start date: 2007-03-27

Other drugs received by patient: Warfarin Sodium; Methylpednisolone Sodium Succinate; Fragmin; Famotidine



Possible Zyvox side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-22

Patient: female, weighing 91.4 kg (201.1 pounds)

Reactions: Drug Interaction, Coagulation Time Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Argatroban
    Dosage: 2 mcg/kg/min,with frequent titration
    Indication: Heparin-Induced Thrombocytopenia
    Start date: 2007-03-25

Argatroban
    Dosage: unk
    End date: 2007-03-31

Other drugs received by patient: Solu-Medrol; Pepcid; Warfarin Sodium; Immune Globulin NOS; Fragmin



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-06-11

Patient:

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
Wellbutrin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zyvox
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Zyvox side effects in 57 year old male

Reported by a pharmacist from Spain on 2012-05-25

Patient: 57 year old male

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Dolantina
    Indication: Analgesic Therapy

Zyvox
    Indication: Pleural Infection

Dolantina
    Dosage: 15 mg, hour
    Indication: Postoperative Analgesia
    Start date: 2011-08-02
    End date: 2011-08-13

Other drugs received by patient: Anidulafungin; Enoxaparin; Actrapid; Midazolam; Amikacin; Meperidine HCL; Meropenem; Propofol



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2012-05-10

Patient: female, weighing 102.7 kg (225.9 pounds)

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Cymbalta
    Dosage: 60 mg, daily
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-20

Bupropion HCL
    Dosage: 150 mg, 3x/day
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-21

Other drugs received by patient: Midazolam; Metoprolol; Metoprolol; Hydrocortisone; Fentanyl; Zolpidem; Diazepam; Amiodarone; Morphine; Simvastatin; Fluoxetine; Diphenhydramine; Venlafaxine



Possible Zyvox side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-03

Patient: female, weighing 106.6 kg (234.5 pounds)

Reactions: Hyperthermia Malignant, Drug Interaction, Serotonin Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Zyvox
    Indication: Pyrexia

Zyvox

Wellbutrin
    Dosage: 75 mg, 2x/day
    Administration route: Oral
    Indication: Serotonin Syndrome

Bupropion HCL
    Dosage: 150 mg, 3x/day
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-21

Cymbalta
    Dosage: 60 mg, daily
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-20

Zyvox
    Indication: Staphylococcal Infection

Zyvox
    Indication: Infection

Wellbutrin
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Acetylsalicylic Acid; Versed; Morphine; Diphenhydramine; Senokot; Mucomyst; Zolpidem; Melatonin; Hydrocortisone; Diazepam; Venlafaxine; Fluoxetine; Amiodarone; Nexium; Atrovent; Simvastatin; Doripenem; Lisinopril; Metoprolol; Coreg; Midazolam; Ditropan; Mirapex; Bumex; Fentanyl



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-04-26

Patient:

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
Zyvox
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Wellbutrin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2012-04-24

Patient: female, weighing 102.7 kg (225.9 pounds)

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Cymbalta
    Dosage: 60 mg, daily
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-20

Bupropion
    Dosage: 150 mg, 3x/day
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-21

Other drugs received by patient: Hydrocortisone; Morphine; Fentanyl; Amiodarone; Metoprolol; Midazolam; Diazepam; Fluoxetine; Zolpidem; Venlafaxine; Diphenhydramine; Metoprolol; Simvastatin



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-04-05

Patient:

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Wellbutrin
    Dosage: unk
    Administration route: Oral



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2012-03-27

Patient: female, weighing 102.7 kg (225.9 pounds)

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Cymbalta
    Dosage: 60 mg, daily
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-20

Ibuprofen
    Dosage: 150 mg, 3x/day
    Administration route: Oral
    Indication: Depression
    End date: 2011-07-21

Other drugs received by patient: Morphine; Metoprolol; Midazolam; Metoprolol; Diazepam; Fentanyl; Simvastatin; Zolpidem; Fluoxetine; Amiodarone; Diphenhydramine; Venlafaxine; Hydrocortisone



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-02-29

Patient:

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-02-27

Patient:

Reactions: Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Adderall 5
    Dosage: unk



Possible Zyvox side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-22

Patient: 65 year old female, weighing 64.0 kg (140.8 pounds)

Reactions: Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: 600 mg, bid
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Zyvox
    Dosage: unk
    Start date: 2008-10-25
    End date: 2009-01-27

Amiodarone HCL
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Torsemide
    Dosage: 10 mg, bid
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29

Spironolactone
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Xipamide
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Other drugs received by patient: Metoprolol Tartrate and Hydrochlorothiazide; Digitoxin INJ; Acetaminophen; Enoxaparin Sodium; Omeprazole; Novalgin; Oxycodone HCL; Amitriptyline HCL; Simvastatin



Possible Zyvox side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-08

Patient: 65 year old female

Reactions: Vomiting, Nausea, Oedema Peripheral, Tongue DRY, Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Xipamide
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Amiodarone HCL
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Torsemide
    Dosage: 10 mg, 2x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-29

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Start date: 2008-10-25
    End date: 2009-01-27

Other drugs received by patient: Amitriptyline; Phenprocoumon; Oxycodone; Novalgin; Paracetamol; Enoxaparin Sodium; Digitoxin; Omeprazole; Metoprolol Tartrate and Hydrochlorothiazide; Simvastatin



Possible Zyvox side effects in 65 year old female

Reported by a physician from Germany on 2012-01-30

Patient: 65 year old female, weighing 64.0 kg (140.8 pounds)

Reactions: Renal Failure, Nephrogenic Anaemia, Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Start date: 2008-10-25
    End date: 2009-01-27

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Novalgin
    Dosage: 500 mg, 3x/day
    Administration route: Oral
    Indication: Pain
    Start date: 2008-09-05
    End date: 2008-10-09

Amiodarone HCL
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Other drugs received by patient possibly interacting with the suspect drug:
Torsemide
    Dosage: 10 mg, 2x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29

Acetaminophen
    Dosage: 1 g, 3x/day
    Administration route: Oral
    Indication: Pain
    Start date: 2008-09-05
    End date: 2008-10-03

Xipamide
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Other drugs received by patient: Metoprolol Tartrate and Hydrochlorothiazide; Enoxaparin Sodium; Digitoxin; Amitriptyline; Omeprazole; Oxycodone; Simvastatin



Possible Zyvox side effects in 65 year old female

Reported by a consumer/non-health professional from Germany on 2012-01-27

Patient: 65 year old female

Reactions: Vomiting, Nausea, Oedema Peripheral, Tongue DRY, Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Torsemide
    Dosage: 10 mg, 2x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-29

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Start date: 2008-10-25
    End date: 2009-01-27

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Amiodarone HCL
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Xipamide
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Other drugs received by patient: Paracetamol; Phenprocoumon; Metoprolol Tartrate and Hydrochlorothiazide; Omeprazole; Enoxaparin Sodium; Oxycodone; Digitoxin; Novalgin; Amitriptyline; Simvastatin



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-01-17

Patient:

Reactions: Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
TPN
    Dosage: unk



Possible Zyvox side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-13

Patient:

Reactions: Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Fentanyl-100
    Dosage: unk



Possible Zyvox side effects in 80 year old female

Reported by a physician from Japan on 2011-12-22

Patient: 80 year old female, weighing 42.0 kg (92.4 pounds)

Reactions: Pancytopenia, Drug Interaction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Teicoplanin
    Dosage: 400 mg, single
    Indication: Staphylococcal Sepsis
    Start date: 2011-09-16
    End date: 2011-11-02

Other drugs received by patient: Calcium Carbonate; Miya BM; Alfarol; Omeprazole; Mucosta; Warfarin



Possible Zyvox side effects in 57 year old male

Reported by a pharmacist from Spain on 2011-12-06

Patient: 57 year old male

Reactions: Drug Interaction, Serotonin Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Dolantina
    Dosage: 15 mg, 1x/day
    Indication: Postoperative Analgesia
    Start date: 2011-08-02
    End date: 2011-08-13

Other drugs received by patient: Meropenem; Anidulafungin; Amikacin; Propofol



Possible Zyvox side effects in

Reported by a consumer/non-health professional from United States on 2011-12-06

Patient:

Reactions: Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Fentanyl
    Dosage: unk



Possible Zyvox side effects in 85 year old male

Reported by a pharmacist from Luxembourg on 2011-11-16

Patient: 85 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Drug Interaction, Respiratory Depression

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
Buprenorphine HCL

Other drugs received by patient: Kalinor Retard; Cozaar; Lasix; Amlodipine Besylate; Enoxaparin Sodium; Tamsulosin



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2011-10-20

Patient:

Reactions: Drug Interaction

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient possibly interacting with the suspect drug:
TPN
    Dosage: unk



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