Comparative Study of Autologous Blood Injection Versus Diluted Epinephrine in Treating Actively Bleeding Gastroduodenal Ulcers
Information source: Zagazig University
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Blood, Injection, Injury Type Phobia; Gastrointestinal Ulcer Haemorrhage; Adverse Reaction to Epinephrine
Intervention: Epinephrine (Drug); Blood (Biological)
Phase: N/A
Status: Completed
Sponsored by: Zagazig University Official(s) and/or principal investigator(s): Mohamed H Emara, MD, Principal Investigator, Affiliation: Tropical Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt
Summary
Endoscopic injection of autologous blood can control bleeding from gastroduodenal ulcers.
Clinical Details
Official title: Endoscopic Injection of Autologous Blood Versus Diluted Epinephrine for Control of Actively Bleeding Gastroduodenal Ulcers
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: hemostasis from the ulcer after injection and/or stoppage of haematemesis and melena one day after the procedure.
Secondary outcome: development of re-bleeding after 24 hours after the procedure (occurrence of hematemesis or melena or drop of hemoglobin level >2gm/dl).
Detailed description:
To test the hypothesis that endoscopic injection of autologous blood is superior to
endoscopic injection of diluted epinephrine in controlling bleeding from gastroduodenal
ulcers.
Eligibility
Minimum age: 16 Years.
Maximum age: 60 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- all adult patients with gastroduodenal ulcer
Exclusion Criteria:
- Patients with non ulcer bleeding.
- Patients with malignancy.
- Patients with bleeding disorders or under coagulation therapy.
- Patients with known allergy to epinephrine.
Locations and Contacts
Zagazig University Hospitals, Zagazig, Sharkia 44519, Egypt
Additional Information
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Starting date: March 2012
Last updated: September 24, 2013
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