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Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation

Information source: ACPM Medical College
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Pediatric Spinal Anesthesia

Phase: N/A

Status: Completed

Sponsored by: ACPM Medical College

Summary

The investigators can summarize intrathecal clonidine can potentiate bupivacaine thereby bringing about better quality and longer duration of analgesia, better sedation and better postoperative outcomes with minimal side effects.

Clinical Details

Official title: Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation

Study design: Observational Model: Case Control, Time Perspective: Prospective

Detailed description: In our Randomized controlled, double blind study involving 30 subjects in two groups; the investigators compared the safety, efficacy and quality of using intrathecal hyperbaric bupivacaine 0. 5% and hyperbaric bupivacaine 0. 5% with clonidine 1g/kg in paediatric patients undergoing surgeries below T8 dermatome. American Society of Anesthesiologists (ASA) Grade I patients aged between 3-10 years were scheduled for the surgeries below T8 dermatome up to two hrs duration. The patients were

randomly allocated in - Group A-who received 0. 5%of hyperbaric Bupivacaine 0. 4mg/kg for 5

to15 kg or 0. 3 mg/kg for more than 15 kg intrathecally. Group B-who received 0. 5%of hyperbaric Bupivacaine 0. 4mg/kg for 5 to15 kg or 0. 3 mg/kg for more than 15 kg and 1µg/kg preservative free clonidine intrathecally. The patients studied across the group did not vary much with respect to age, weight and sex distribution.

Eligibility

Minimum age: 3 Years. Maximum age: 10 Years. Gender(s): Both.

Criteria:

Inclusion Criteria: 1. ASA grade-1 physical status. 2. weight 5-35kg 3. age-3 to 10 yrs Exclusion Criteria: 1. patients with known sensitivity to drugs to be used. 2. gross spinal deformity 3. patients in whom regional anesthesia is contraindicated. 4. patients with peripheral neuropathy. 5. patient with hemodynamic instability.

Locations and Contacts

Additional Information

Starting date: November 2009
Last updated: August 9, 2012

Page last updated: August 20, 2015

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