Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation
Information source: ACPM Medical College
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Pediatric Spinal Anesthesia
Phase: N/A
Status: Completed
Sponsored by: ACPM Medical College
Summary
The investigators can summarize intrathecal clonidine can potentiate bupivacaine thereby
bringing about better quality and longer duration of analgesia, better sedation and better
postoperative outcomes with minimal side effects.
Clinical Details
Official title: Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation
Study design: Observational Model: Case Control, Time Perspective: Prospective
Detailed description:
In our Randomized controlled, double blind study involving 30 subjects in two groups; the
investigators compared the safety, efficacy and quality of using intrathecal hyperbaric
bupivacaine 0. 5% and hyperbaric bupivacaine 0. 5% with clonidine 1µg/kg in paediatric
patients undergoing surgeries below T8 dermatome.
American Society of Anesthesiologists (ASA) Grade I patients aged between 3-10 years were
scheduled for the surgeries below T8 dermatome up to two hrs duration. The patients were
randomly allocated in - Group A-who received 0. 5%of hyperbaric Bupivacaine 0. 4mg/kg for 5
to15 kg or 0. 3 mg/kg for more than 15 kg intrathecally.
Group B-who received 0. 5%of hyperbaric Bupivacaine 0. 4mg/kg for 5 to15 kg or 0. 3 mg/kg for
more than 15 kg and 1µg/kg preservative free clonidine intrathecally.
The patients studied across the group did not vary much with respect to age, weight and sex
distribution.
Eligibility
Minimum age: 3 Years.
Maximum age: 10 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
1. ASA grade-1 physical status.
2. weight 5-35kg
3. age-3 to 10 yrs
Exclusion Criteria:
1. patients with known sensitivity to drugs to be used.
2. gross spinal deformity
3. patients in whom regional anesthesia is contraindicated.
4. patients with peripheral neuropathy.
5. patient with hemodynamic instability.
Locations and Contacts
Additional Information
Starting date: November 2009
Last updated: August 9, 2012
|
