Escalating Ketamine Doses and Pre-emption
Information source: Tel-Aviv Sourasky Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Postoperative Pain Management
Intervention: Ketamine (Drug); ketamine (Drug); ketamine (Drug)
Phase: N/A
Status: Completed
Sponsored by: Tel-Aviv Sourasky Medical Center
Summary
Ketamine affects postoperative pain when administered intravenously immediately before,
during or at the end of surgical procedures. We assessed the effects of multiple and
escalating doses of ketamine administered many hours before surgery on postoperative pain
and analgesia consumption.
Clinical Details
Official title: EARLY PREOPERATIVE ESCALATING DOSES OF KETAMINE ATTENUATE POSTOPERATIVE PAIN AND REDUCE MORPHINE CONSUMPTION IN HUMANS
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Primary outcome: postoperative pain
Secondary outcome: opioid drug consumption
Eligibility
Minimum age: 15 Years.
Maximum age: 75 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
Consecutive patients, who were scheduled to undergo general or orthopedic oncologic
surgery under general anesthesia
Exclusion Criteria:
1. allergy to opioids, ketamine or non-steroidal anti-inflammatory drugs (NSAIDs)
2. history of lasting chronic pain or psychiatric disorders or had used opioids or
psychotropic drugs of any sort during the past two weeks
3. soldiers and pregnant women
Locations and Contacts
Tel Aviv Medical Center, Tel Aviv, Israel
Additional Information
Starting date: January 2007
Last updated: February 16, 2010
|
