Protein, Amino Acids & Insulin & Glucagon Secretion in Humans
Information source: Minneapolis Veterans Affairs Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Type 2 Diabetes; Metabolic Syndrome
Intervention: water, glucose with or without amino acid (Other)
Phase: N/A
Status: Recruiting
Sponsored by: Minneapolis Veterans Affairs Medical Center Official(s) and/or principal investigator(s):
Frank Q Nuttall, M.D., Ph.D., Principal Investigator, Affiliation: Minneapolis VA Health Care System
Overall contact:
Frank Q Nuttall, M.D., Ph.D., Phone: 612-467-4424, Email: nutta001@umn.edu
Summary
The purpose of this study is to determine the effect of various foods and/or food substances
such as fats or proteins on the blood glucose and insulin concentrations in people with and
without type 2 diabetes.
Clinical Details
Official title: The Effect of Ingestion of Foods on the Plasma Glucose and Insulin Response in Subjects With Type 2 Diabetes: Protein, Amino Acids & Insulin & Glucagon Secretion in Humans
Study design: Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject)
Primary outcome: Change in blood glucose concentration
Secondary outcome: Change in serum insulin concentration
Detailed description:
Various foods or food substances are given as a test meal. The metabolic response is
determined at various times after the administration of the meal (e. g. blood glucose, and
other hormones and metabolites).
Eligibility
Minimum age: 18 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Subjects with or without type 2 diabetes
- C-Peptide > 1. 5 ng/ml
- Able to come to the Minneapolis VA Medical Center on several occasions over 2-4 weeks
Exclusion Criteria:
- Body mass index > 40
- hematologic abnormalities
- liver disease
- kidney disease
- congestive heart failure
- life threatening malignancies
Locations and Contacts
Frank Q Nuttall, M.D., Ph.D., Phone: 612-467-4424, Email: nutta001@umn.edu
Minneapolis VA Health Care System, Minneapolis, Minnesota 55417, United States; Recruiting
Frank Q Nuttall, M.D., Ph.D., Phone: 612-467-4424, Email: nutta001@umn.edu
Mary C. Gannon, Ph.D., Phone: 612/467-2895, Email: ganno004@umn.edu
Frank Q Nuttall, M.D, Ph.D., Principal Investigator
Additional Information
Starting date: August 1982
Last updated: November 18, 2011
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