DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate

Information source: University of Mississippi Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Hypertension

Intervention: Metoprolol (Drug); Nebivolol (Drug)

Phase: N/A

Status: Terminated

Sponsored by: University of Mississippi Medical Center

Official(s) and/or principal investigator(s):
Deborah Minor, PharmD, Principal Investigator, Affiliation: University of Mississippi Medical Center

Summary

The purpose of the study is to compare the effects of nebivolol and metoprolol on 24-hour ambulatory blood pressure characteristics and basal metabolic rates in patients with hypertension.

Clinical Details

Official title: Comparative Effects of Nebivolol Versus Metoprolol on 24-hour Blood Pressures and Basal Metabolic Rate: An Open-Label Study

Study design: Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: Primary Outcome is Pre- and Post-treatment Ambulatory Blood Pressure.

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- 18 years old or older

- currently be treated at a University of MS Medical Center Internal Medicine Clinics

- currently taking metoprolol succinate for hypertension

- have their hypertension controlled (<140/90).

Exclusion Criteria:

- uncontrolled hypertension

- severe renal or moderate hepatic impairment

- currently taking CYP 2D6 inducers/inhibitors

- recent stroke (less than 6 months)

- recent myocardial infarction (less than 6 months)

- congestive heart failure

- diagnosed obstructive sleep apnea

- atrial fibrillation

- arm circumference >50 cm

Locations and Contacts

University of Mississippi Medical Center, Jackson, Mississippi 39216, United States
Additional Information

Starting date: January 2009
Last updated: March 18, 2013

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017