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Dexmedetomidine in Spinal Anesthesia

Information source: Inje University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Blood Pressure; Anxiety

Intervention: Dexmedetomidine (Drug); Dexmedetomidine with heavy bupivacaine (Drug)

Phase: N/A

Status: Completed

Sponsored by: Inje University

Official(s) and/or principal investigator(s):
Ki Hwa Lee, MD, Principal Investigator, Affiliation: Inje University

Summary

Patients were randomized into two groups, A group and B group. A group and B group patients are injected intravenous dexmedetomidine after intrathecal injection (IT) of heavy bupivacaine and injected intravenous dexmedetomidine before IT of heavy bupivacaine, respectively. The investigators will compare of hemodynamics and patient's comfortability between two groups.

Clinical Details

Official title: Hemodynamic Effect of Dexmedetomidine on Heavy Bupivacaine Spinal Anesthesia

Study design: Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)

Primary outcome: Hemodynamic effects

Secondary outcome: Patient's comfortability and anxiety

Detailed description: A and B group patients will intravenous inject dexmedetomidine 1mcg/kg for 10 minute loading infusion and 0. 2mcg/kg/hr for continuous infusion. A group receive intravenous dexmedetomidine after procedure, and B group receive intravenous dexmedetomidine before procedure. Both group patients will hydrate 6 ml/kg crystalloid solution and will evaluated patient's anxiety and comfortability perioperative period. Vital signs will record 5 minutes interval at operating room and post-anesthetic care units.

Eligibility

Minimum age: 20 Years. Maximum age: 60 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- 20 - 60 aged patients

- orthopedic operation undergoing spinal anesthesia

Exclusion Criteria:

- more than American society of anesthesiologists classification 3

- hypertension

- diabetes mellitus

- heart disease (bradycardia, atrioventricular block)

Locations and Contacts

Inje University, Haeundae paik hospital, Busan 612-896, Korea, Republic of
Additional Information

Starting date: March 2014
Last updated: August 9, 2015

Page last updated: August 23, 2015

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