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To Compare Therapeutic Effect of Intravitreal Bevacizumab and Triamcinolone in Resistant Uveitic Cystoid Macular Edema

Information source: Shahid Beheshti Medical University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Resistant Cystoid Macular Edema

Intervention: Intravitreal injection of Triamcinolone (Drug); Intravitreal injection of Avastin (Drug)

Phase: Phase 1

Status: Active, not recruiting

Sponsored by: Shahid Beheshti Medical University

Official(s) and/or principal investigator(s):
Masoud Soheilian, MD, Principal Investigator, Affiliation: Ophthalmic Research Center of Shaheed Beheshti Medical University

Summary

Cystoid macular edema (CME) is one of the common causes of vision loss in patients with UveitiS .Triamcinolone has been effectively used in reducing CME and improving the vision. Also there are some documents which recommend Bevacizumab(avastin) could reduce macular edema. This study compare intravitreous injection of triamcinolone and avastin in patients with resistant uveitic cystoid macular edema.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Primary outcome:

Resorbed CME in OCT

Resorbed CME in clinical examination

Secondary outcome: need to retreatment

Detailed description: This study compare intravitreous injection of triamcinolone and avastin in patients with resistant uveitic cystoid macular edema.

Eligibility

Minimum age: N/A. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Uveitic CME

- Uveitic CME refractory to routine treatment

- Vision better than 5/200 and worse than 20/50

Exclusion Criteria:

- Mono- Ocular patients

- History of vitrectomy

- Glaucoma or ocular hypertension

- History of other retinal disease that can cause macular edema

- Pregnancy

- Significant media opacity

- Vision better than 20/50

Locations and Contacts

Masoud Soheilian , MD, Tehran 16666, Iran, Islamic Republic of
Additional Information

Starting date: August 2006
Last updated: July 28, 2008

Page last updated: August 23, 2015

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