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Continuous Subacromial Bupivacaine

Information source: Turku University Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Shoulder Arthroscopy

Intervention: bupivacaine (Drug)

Phase: N/A

Status: Completed

Sponsored by: Turku University Hospital


The investigators wanted to re-evaluate the effects of subacromial bupivacaine infusion after shoulder arthroscopy with standard surgical techniques, including rotator cuff operations. The investigators hypothesized that patients having 5. 0 mg/ml bupivacaine infusion at a rate of 2 ml/h subacromially would need less opioids than patients receiving a placebo infusion.

Clinical Details

Official title: The Analgesic Effect of Continuous Subacromial Bupivacaine Infusion After Arthroscopic Shoulder Surgery: a Randomized Controlled Trial

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: The consumption of analgesics (oxycodone)

Secondary outcome: The intensity of pain

Detailed description: Shoulder surgery has become a routine outpatient procedure. Previously shoulder surgery was associated with intense, occasionally severe postoperative pain and hence considerable use of opioids. Also arthroscopic shoulder surgery, especially rotator cuff procedures, may cause significant pain resulting sometimes in inpatient admission. Subacromial local anaesthetic infusion as a part of a multimodal approach is one commonly used modality to pain relief after shoulder surgery. Nevertheless, it has been criticized recently for its poor benefits and possible adverse effects. On the whole, the scientific evidence of the advantages of local anaesthetic infusions is inconclusive.


Minimum age: 20 Years. Maximum age: 70 Years. Gender(s): Both.


Inclusion Criteria:

- subacromial impingement disease

- scheduled for an elective arthroscopic surgery

Exclusion Criteria:

- liver disease

- renal impairment

- psychiatric disorder

- alcohol abuse

- obesity (a body mass index of > 35 kg/m2)

- allergies to the drugs used in the study

Locations and Contacts

Turku University Hospital and University of Turku, Turku, Finland
Additional Information

Starting date: January 2009
Last updated: June 21, 2011

Page last updated: August 23, 2015

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