Non- Essential Amino Acid Requirements and Metabolism in Humans
Information source: University of British Columbia
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Healthy Adult Males
Phase: N/A
Status: Completed
Sponsored by: University of British Columbia Official(s) and/or principal investigator(s):
Rajavel Elango, Ph.D, Principal Investigator, Affiliation: University of British Columbia
Summary
Protein is a major structural component of all cells in the body. The nutritional importance
of protein is because of their amino acids. 9 are called essential and 11 are called
non-essential, based on whether we need to get them from diet. This classification is based
on studies done using older techniques. Recent studies suggest that these so called
non-essential amino acids play important roles in our body's health. For the first time,
this proposal defines an experimental design to examine non- essential amino acid/nitrogen
requirements and metabolism in humans using the Indicator Amino Acid Oxidation (IAAO)
technique.
The objective of the current study is to examine the application of IAAO technique to
determine the non-essential amino acid/nitrogen requirement in adult humans.
Clinical Details
Official title: Application of Indicator Amino Acid Oxidation Technique to Determine Non-essential Amino Acids/Nitrogen Requirements in Adult Humans
Study design: Observational Model: Cohort, Time Perspective: Prospective
Primary outcome: 13 Carbon dioxide production
Eligibility
Minimum age: 20 Years.
Maximum age: 40 Years.
Gender(s): Male.
Criteria:
Inclusion Criteria:
- 20-40 years of age
- Male
- Classified as normal body weight based on body mass index (BMI) 18. 5-25kg/m2
- Free of any concurrent illness
Exclusion Criteria:
- Men not in good health or have a metabolic, neurological, genetic or immune disorder
including diabetes and hypertension
- Men who are classified as underweight(<18. 5kg/m2), overweight(25-30kg/m2) or obese
(>30kg/m2) using the BMI classification)
- Men who are allergic to milk, eggs and egg protein
Locations and Contacts
Child and Family Research Institute, Vancouver, British Columbia V5Z4H4, Canada
Additional Information
Starting date: October 2013
Last updated: May 29, 2015
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