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Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat

Information source: Seoul National University Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Pharyngitis

Intervention: Dexamethasone (Drug); Paracetamol (Drug)

Phase: N/A

Status: Not yet recruiting

Sponsored by: Seoul National University Hospital

Official(s) and/or principal investigator(s):
Hee-Pyoung Park, PhD, Principal Investigator, Affiliation: Seoul National University of Hospital

Overall contact:
Hyun-Chang Kim, MD, Phone: 82-10-2886-2876, Email: onidori1979@gmail.com

Summary

The investigators want to evaluate the efficacy of the dexamethasone and paracetamol for the prevention of postoperative sore throat.

Clinical Details

Official title: Combined Effect of Preoperative Dexamethasone and Intraoperative Paracetamol on Postoperative Sore Throat for Patients Undergoing Urologic Surgery

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Primary outcome: Postoperative sore throat

Secondary outcome:

Postoperative sore throat degree

Postoperative pain

Nausea

Vomiting

Somnolence

Shivering

Headache

Hoarseness

Dysphagia

Analgesics

Postoperative sore throat

Detailed description: The postoperative sore throat is a common complication after the general anesthesia which decreases the quality of life. Dexamethasone is known to effective for the prevention of postoperative sore throat. The combined effect of the dexamethasone and paracetamol for postoperative sore throat, however, is not investigated. The investigators want to evaluate the efficacy of the dexamethasone and paracetamol for the prevention of postoperative sore throat.

Eligibility

Minimum age: 19 Years. Maximum age: 80 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patients scheduled for urologic surgery under general anesthesia

- ASA I-III

Exclusion Criteria:

- Patients with recent sore throat

- Patients with neck surgery

- Patients with anticipated difficult airway

- Patients with Mallampati grade 3

- Patients with severe cardiovascular or pulmonary disease

- Patients with allergic history to dexamethasone or paracetamol

- Patients with liver function disorder

- Patients with liver disease

Locations and Contacts

Hyun-Chang Kim, MD, Phone: 82-10-2886-2876, Email: onidori1979@gmail.com

Seolu National University of Hospital, Seoul, Korea, Republic of; Not yet recruiting
Hyun-Chang Kim, MD, Phone: 83-10-2886-2876, Email: onidori1979@gmail.com
Additional Information

Starting date: October 2014
Last updated: October 16, 2014

Page last updated: August 23, 2015

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