The objective of this study is to demonstrate the effectiveness and tolerability of the
buprenorphine transdermal system (20 mg) in comparison to the buprenorphine transdermal
system (5 mg) and oxycodone immediate release in subjects with moderate to severe
osteoarthritis pain currently treated with oral opioids. The double-blind treatment
intervention duration is 12 weeks during which time supplemental analgesic medication
(acetaminophen, ibuprofen, immediate release oxycodone) will be provided to all subjects in
addition to study drug.
Minimum age: 40 Years.
Maximum age: N/A.
Gender(s): Both.
Parkway Medical Center, Birmingham, Alabama 35215, United States
International Clinical Research Network, Chula Vista, California 91910, United States
Clinical Trials Research, Roseville, California 95661, United States
Accelovance, San Diego, California 92108, United States
Torrance Clinical Research, Torrance, California 90505, United States
Southern Colorado Clinic, Pueblo, Colorado 81008, United States
Drug Study Institute, Jupiter, Florida 33458, United States
Innovative Research of West Florida, Inc., Largo, Florida 33770, United States
International Medical Research, Ormond Beach, Florida 32174, United States
Peninsula Research, Inc., Ormond Beach, Florida 32174, United States
Palm Beach Research Center, West Palm Beach, Florida 33409, United States
Georgia Medical Research Institute, Marietta, Georgia 30060, United States
Non- Surgical Orthopedic & Spine Center, P.C., Marietta, Georgia 30060, United States
The Arthritis Center, Springfield, Illinois 62704, United States
Commonwealth Biomedical Research, LLC, Madisonville, Kentucky 42431, United States
Miray Medical Center, Brockton, Massachusetts 23010, United States
Professional Clinical Research Crystal Lake Health Center, Benzonia, Michigan 49616, United States
Rheumatology PC, Kalamazoo, Michigan 49009, United States
Pharm Quest, Greensboro, North Carolina 27401, United States
The Clinical Trial Center, LLC, Jenkintown, Pennsylvania 19046, United States
Amarillo Center for Clinical Research, Amarillo, Texas 79124, United States
Med Search Professional Group/Pharmaceutical C-Trials Inc., Hurst, Texas 76054, United States
Texas Medical Research Associates, San Antonio, Texas 78238, United States