Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of
Information source: Tehran University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Sore Throat; Cough
Intervention: betamethasone gel (Drug); lidocaine jelly (Drug); distilled water (Drug)
Phase: Phase 3
Status: Completed
Sponsored by: Tehran University of Medical Sciences
Summary
ABSTRACT:
The aim of this study was to investigate the effect of betamethasone gel and lidocaine jelly
(over tracheal tube cuff) compared with distilled water on the post intubation syndrome
incidence. This study has not been carried out in Iran.
99 patients of either sex undergoing elective surgery were recruited in a single blind
randomized study. The patients, using randomization table, were divided into three groups.
Anesthetics and medications used during surgery were similar for all the patients.
For the all patients, the incidence of postoperative sore throat, cough and hoarseness of
the voice in the different follow-up periods (1, 6 and 24 hours) based on the different
types of medications were obtained.
Clinical Details
Official title: Effect of Betamethasone Gel and Lidocaine Jelly Applied Over Tracheal Tube Cuff on Post Operative Sore Throat, Cough and Hoarseness of Voice on the Patients
Study design: Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Caregiver), Primary Purpose: Treatment
Primary outcome: sore throatcough hoarseness of voice sore throat sore throat cough cough hoarseness of voice hoarseness of voice
Eligibility
Minimum age: 15 Years.
Maximum age: 50 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
1. 50 years15 years
2. no acute upper respiratory infections and no sore throat
3. candidate for elective surgery unrelated to the throat
4. The lack of airways difficulties
5. candidate for general anesthesia with intubation
6. no contraindications for receiving steroid
7. surgery time < 240 minutes
8. intubation up to 2 times
9. tracheal tube cuff pressure = 25-30 cm H2o
10. fasting for 8-6 hours prior to surgery
11. ASA I and ASAII and
12. Surgery under general anesthesia and endotracheal intubation
Exclusion Criteria:
1. use of nasogastric tube or throat packs
2. patients with upper respiratory tract infection
3. patients on steroid therapy were excluded from the study
Locations and Contacts
Department of Anesthesiology, Booali Hospital, Islamic Azad University,, Tehran, Iran, Islamic Republic of
Additional Information
Starting date: March 2012
Last updated: April 14, 2014
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