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The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis

Information source: Shanghai Jiao Tong University School of Medicine
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Hemodialysis

Intervention: acetylsalicylic acid (Drug)

Phase: N/A

Status: Completed

Sponsored by: Shanghai Jiao Tong University School of Medicine

Summary

The aim of present study is to examine the effect of low-dose aspirin on the incidence of cardiovascular events and mortality in patients undergoing chronic hemodialysis.

Clinical Details

Official title: The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis

Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Primary outcome: survival rate

Secondary outcome: cardio-cerebral event

Detailed description: This study prospectively evaluate the impacts of low dose aspirin on survival and cardio-cerebral vascular events in a large cohort of Chinese patients undergoing chronic hemodialysis. Between January 2008, consecutive patients with hemodialysis with aspirin were enrolled. We examine the association of aspirin with all-cause mortality in patients matched by propensity scores using the Kaplan-Meier method and Cox models in "intention-to-treat" analyses. The secondary endpoint was rate of cardio-cerebral events.

Eligibility

Minimum age: 18 Years. Maximum age: 85 Years. Gender(s): Both.

Criteria:

Inclusion Criteria: All patients aged 18 to 85, undergoing chronic hemodialysis, who have none of the following exclusion criteria. Exclusion Criteria: History of gastric or duodenal ulcers Known allergy to aspirin or other NSAIDs

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Locations and Contacts

Additional Information

Starting date: January 2008
Last updated: October 22, 2014

Page last updated: August 20, 2015

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