The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis
Information source: Shanghai Jiao Tong University School of Medicine
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Hemodialysis
Intervention: acetylsalicylic acid (Drug)
Phase: N/A
Status: Completed
Sponsored by: Shanghai Jiao Tong University School of Medicine
Summary
The aim of present study is to examine the effect of low-dose aspirin on the incidence of
cardiovascular events and mortality in patients undergoing chronic hemodialysis.
Clinical Details
Official title: The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis
Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Primary outcome: survival rate
Secondary outcome: cardio-cerebral event
Detailed description:
This study prospectively evaluate the impacts of low dose aspirin on survival and
cardio-cerebral vascular events in a large cohort of Chinese patients undergoing chronic
hemodialysis. Between January 2008, consecutive patients with hemodialysis with aspirin were
enrolled. We examine the association of aspirin with all-cause mortality in patients matched
by propensity scores using the Kaplan-Meier method and Cox models in "intention-to-treat"
analyses. The secondary endpoint was rate of cardio-cerebral events.
Eligibility
Minimum age: 18 Years.
Maximum age: 85 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
All patients aged 18 to 85, undergoing chronic hemodialysis, who have none of the
following exclusion criteria.
Exclusion Criteria:
History of gastric or duodenal ulcers Known allergy to aspirin or other NSAIDs
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Locations and Contacts
Additional Information
Starting date: January 2008
Last updated: October 22, 2014
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