Branched Chain Aminoacid Supplementation in Patients With Liver Cirrhosis
Information source: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Liver Cirrhosis
Intervention: Branched-chain aminoacids (Dietary Supplement); High-fiber high protein diet (Other)
Phase: Phase 4
Status: Completed
Sponsored by: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Summary
Malnutrition is a frequent complication in patients with liver cirrhosis. Most patients have
decreased dietary intake due to ascites, hepatic encephalopathy and pro-inflammatory
cytokines.
We hypothesized that branched chain aminoacids can improve nutritional status and delay
episodes of hepatic encephalopathy
Clinical Details
Official title: High-fiber High-fiber Diet and Branched Chain Aminoacids. Impact on Nutritional Status and Complications in Patients With Liver Cirrhosis
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: Nutritional status
Secondary outcome: Hepatic Encephalopathy
Eligibility
Minimum age: 18 Years.
Maximum age: 75 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
Ambulatory patients Patients with confirmed diagnose of liver cirrhosis Patients
classified as Child-Pugh A or Child Pugh B
Exclusion Criteria:
Acute or chronic renal failure Pregnancy Overt hepatic encephalopathy
Locations and Contacts
Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico city 14000, Mexico
Additional Information
Starting date: January 2011
Last updated: December 23, 2013
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