DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Postpartum Thyroid Measures and Mood

Information source: Oklahoma State University Center for Health Sciences
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Postpartum Depression

Phase: N/A

Status: Completed

Sponsored by: Oklahoma State University Center for Health Sciences

Official(s) and/or principal investigator(s):
Gary H. Watson, PhD, Study Director, Affiliation: Philadelphia College of Osteopathic Medicine Georgia Campus

Summary

Women with abnormal serum thyroid antibody levels or abnormal TSH and/or T4 values are more likely than their normal counterparts to have higher scores on a common postpartum depression screening test.

Clinical Details

Official title: Postpartum Thyroid Measures and Mood

Study design: Observational Model: Cohort, Time Perspective: Prospective

Primary outcome: Numerical score on the Edinburgh Postnatal Depression Scale

Detailed description: This small pilot study was an attempt to corroborate a relationship between quantified mood and thyroid measures, using the numerical scores obtained from a common depression screen, the Edinburgh Postnatal Depression Scale (EPDS), as a continuum. Mood scores were compared with presence of thyroid autoantibodies and plasma concentrations of free T4 and TSH.

Eligibility

Minimum age: 18 Years. Maximum age: 50 Years. Gender(s): Female.

Criteria:

Inclusion Criteria:

- Over 18 years of age

- In third trimester of pregnancy when recruited

- Negative for the following drugs detected by a urine drug screen:

- Amphetamines

- Barbiturates

- Benzodiazepines

- Cocaine

- Opiates

- Phencyclidine metabolites (PCP), and tricyclic antidepressants

- Vaginal delivery

- Screened negative for major depressive disorder on the Edinburgh Postnatal

Depression Scale (EPDS) at her prenatal enrollment in the study

- Receiving a score of 12 or lower out of a possible 30

Exclusion Criteria:

- Under age 18

- Positive for any of the following drugs:

- Amphetamines

- Barbiturates

- Benzodiazepines

- Cocaine

- Opiates

- Phencyclidine metabolites (PCP), and tricyclic antidepressants

- Cesarean delivery

- EPDS score over 12 at prenatal screening test

Locations and Contacts

Oklahoma State University Center for Health Sciences Houston Park Obstetrics Clinic, Tulsa, Oklahoma 74107, United States
Additional Information

Starting date: January 2000
Last updated: January 26, 2010

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017