Psoriasis is a chronic, often severe, autoimmune condition that affects approximately 2% of
the world's population. The epidemiology of pediatric psoriasis has not been well documented
and no treatment guidelines exist for pediatric psoriasis.
Etanercept is a biologic drug and has been licensed for the treatment of chronic severe
plaque psoriasis in children and adolescents (8-17 years of age) who are inadequately
controlled by or are intolerant to, other systemic therapies or phototherapies. Although the
long-term safety and efficacy of etanercept in children with juvenile idiopathic arthritis
(JIA) has been studied and the short-term safety profile of etanercept in both JIA and
pediatric psoriasis appears similar, there is limited data available about the long-term
effects of etanercept in pediatric psoriasis, especially with respect to malignancy. The aim
of this study is to assess the safety and effectiveness of etanercept for the treatment of
pediatric psoriasis in Europe. Patients aged 4-17 with plaque psoriasis diagnosed by a
dermatologist will be invited to participate in the registry only after a clinical decision
has been made to prescribe etanercept. The safety of the drug and how well the drug works
will be evaluated during the follow-up period. The follow-up period will last 5 years and
patients will be followed up every 3 months for the first 2 years and every 6 months for the
next 3 years.
Minimum age: 6 Years.
Maximum age: 17 Years.
Gender(s): Both.
Centre Hospitalier Victor Dupouy / Service de Dermatologie, Argenteuil Cedex 95107, France
Hopital Trousseau, Service de Dermatologie, Chambray-lès-Tours 37170, France
CHU de Nantes - Hôtel Dieu, Nantes 44093, France
Service de Dermatologie, Quimper 29107, France
Klinik fuer Dermatologie, Allergologie und Venerologie, Berlin 10117, Germany
Universitatsklinikum der TU Dresden Carl Gustav CarusKlinik, Dresden 01307, Germany
Universitätsklinikum Hartmmannstrasse 14 Erlangen 91052, Erlangen 91052, Germany
Universitätsklinikum Hufelandstr. 55 Essen 45147, Essen 45122, Germany
J W Goethe Universitaet Frankfurt, Frankfurt am Main 60590, Germany
Kath. Kinderkrankenhaus Wilhelmstift, Hamburg 22149, Germany
Universitaetsklinik Koeln, Köln 50937, Germany
Kinderklinik der Johannes-Gutenberg Universitat Mainz, Mainz 55101, Germany
Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin 53757, Germany
University of Athens Andreas Syngros Hospital Athens, Greece, Athens 16121, Greece
Hospital for Skin and Venereal Diseases, Thessaloniki 54644, Greece
Heim Pal Children's Hospital, Budapest 1089, Hungary
Universita degli Studi di Napoli, Napoli 80131, Italy
University of Padova, Padova 35128, Italy
U.O. di Dermatologia ARNAS, Palermo 90100, Italy
Cattedra Policlinico Gemelli, Roma 00168, Italy
Ospedale Alfredo Fiorini, Terracina 04019, Italy
UMC St Radbound, Nijmegen 6500 HB, Netherlands
Erasmus MC, Rotterdam 3000 CA, Netherlands
Hospital Santa Maria, Lisboa 1649-028, Portugal
Hospital de la Santa Cruz y San Pablo, Barcelona 08025, Spain
Hospital Parc Tauli, Barcelona 08208, Spain
Hospital La Paz, Madrid 28046, Spain