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Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)

Information source: Hormozgan University of Medical Sciences
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Surgical Site Infections

Intervention: Cefazolin irrigation (Other); Normal Saline Irrigation (Other)

Phase: N/A

Status: Completed

Sponsored by: Hormozgan University of Medical Sciences

Official(s) and/or principal investigator(s):
Maryam Rahmani, MD, Study Director, Affiliation: Hormozgan University of Medical Sciences


This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs. Hypothesis: Normal saline or cefazolin irrigation decreases the incidence of SSIs.

Clinical Details

Official title: Comparison of the Effect of Cefazolin and Normal Saline Irrigation With no Irrigation on the Incidence of Surgical Site Infections

Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Primary outcome: SSI

Detailed description: All pregnant women who underwent cesarean after 6 hours passed their rupture of membrane and attended to Shariati Hospital of Bandarabbass were eligible for our study.


Minimum age: N/A. Maximum age: N/A. Gender(s): Female.


Inclusion Criteria:

- pregnant women

- 6 hours passed their rupture of membrane

- needed to undergo cesarean

Exclusion Criteria:

- allergy to penicillin

- allergy to cefazolin

- history of immunosuppressive drug use

- gestational diabetes mellitus

- preeclampsia

Locations and Contacts

Shariati Hospital, Bandar `Abbas, Hormozgan 79176, Iran, Islamic Republic of
Additional Information

Starting date: December 2010
Last updated: October 12, 2012

Page last updated: August 20, 2015

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