The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
Information source: Presbyterian Church East Africa Kikuyu Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cataract; Endophthalmitis
Intervention: cefuroxime (Drug); Saline placebo (Drug)
Phase: N/A
Status: Completed
Sponsored by: Presbyterian Church East Africa Kikuyu Hospital Official(s) and/or principal investigator(s): Dan Gradin, MD, Principal Investigator, Affiliation: PCEA Kikuyu Hospital
Summary
The study investigates whether placing an antibiotic inside the eye at the end of cataract
surgery in children will reduce the amount of fibrin formation (fibrin formation can block
the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level
infection and could be prevented by the antibiotic.
Clinical Details
Official title: The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Fibrin formation in anterior chamber
Detailed description:
The study investigates whether using an antibiotic (cefuroxime) in the anterior chamber of
the eye at the end of surgery for cataract in children will reduce the amount of fibrin
formation.
Eligibility
Minimum age: 6 Months.
Maximum age: 15 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- bilateral congenital or developmental pediatric cataract
Exclusion Criteria:
- traumatic cataract
Locations and Contacts
Presbyterian Church East Africa Kikuyu Hospital, Kikuyu 00902, Kenya
Additional Information
Starting date: February 2008
Last updated: August 7, 2008
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