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The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery

Information source: Presbyterian Church East Africa Kikuyu Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cataract; Endophthalmitis

Intervention: cefuroxime (Drug); Saline placebo (Drug)

Phase: N/A

Status: Completed

Sponsored by: Presbyterian Church East Africa Kikuyu Hospital

Official(s) and/or principal investigator(s):
Dan Gradin, MD, Principal Investigator, Affiliation: PCEA Kikuyu Hospital

Summary

The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level infection and could be prevented by the antibiotic.

Clinical Details

Official title: The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Fibrin formation in anterior chamber

Detailed description: The study investigates whether using an antibiotic (cefuroxime) in the anterior chamber of the eye at the end of surgery for cataract in children will reduce the amount of fibrin formation.

Eligibility

Minimum age: 6 Months. Maximum age: 15 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- bilateral congenital or developmental pediatric cataract

Exclusion Criteria:

- traumatic cataract

Locations and Contacts

Presbyterian Church East Africa Kikuyu Hospital, Kikuyu 00902, Kenya
Additional Information

Starting date: February 2008
Last updated: August 7, 2008

Page last updated: August 23, 2015

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