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Heparin Dose for Radial Angiography

Information source: University of Alberta
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Coronary Angiograph

Intervention: unfractionated heparin (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: University of Alberta

Summary

At present, coronary angiogram is usually performed either through an artery in your groin or wrist. An important limitation of the wrist approach is an increase rate of blockage of the wrist artery. It is possible that the dose of blood thinner (i. e. heparin) may decrease the risk of blockage. Early studies seem to suggest that higher dose is required to reduce the risk of this important complication. However, to date there has not been a definitive study to determine the most appropriate heparin dose for the prevention of this complication. The main goal of this study is to determine the appropriate heparin dose to prevent wrist artery blockage and to determine risk factors for developing such a complication.

Clinical Details

Official title: Low Versus High Dose Unfractionated Heparin in Patients Undergoing Angiography Via the Radial Artery

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: radial artery occlusion

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patients older than 18 years of age who were referred for either urgent or elective

cardiac catheterization were eligible for the study if a normal Allen's test was demonstrated Exclusion Criteria:

- myocardial infarction with shock,

- ST-elevation myocardial infarction,

- patients undergoing planned percutaneous coronary intervention, and

- patients in whom transradial approach is contraindicated such as hemodialysis

patients

Locations and Contacts

Mazankowski Alberta Heart Institute, Edmonton, Alberta T6G2B7, Canada
Additional Information

Starting date: July 2008
Last updated: July 2, 2012

Page last updated: August 23, 2015

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