Heparin Dose for Radial Angiography
Information source: University of Alberta
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Coronary Angiograph
Intervention: unfractionated heparin (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: University of Alberta
Summary
At present, coronary angiogram is usually performed either through an artery in your groin
or wrist. An important limitation of the wrist approach is an increase rate of blockage of
the wrist artery. It is possible that the dose of blood thinner (i. e. heparin) may decrease
the risk of blockage. Early studies seem to suggest that higher dose is required to reduce
the risk of this important complication. However, to date there has not been a definitive
study to determine the most appropriate heparin dose for the prevention of this
complication. The main goal of this study is to determine the appropriate heparin dose to
prevent wrist artery blockage and to determine risk factors for developing such a
complication.
Clinical Details
Official title: Low Versus High Dose Unfractionated Heparin in Patients Undergoing Angiography Via the Radial Artery
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: radial artery occlusion
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients older than 18 years of age who were referred for either urgent or elective
cardiac catheterization were eligible for the study if a normal Allen's test was
demonstrated
Exclusion Criteria:
- myocardial infarction with shock,
- ST-elevation myocardial infarction,
- patients undergoing planned percutaneous coronary intervention, and
- patients in whom transradial approach is contraindicated such as hemodialysis
patients
Locations and Contacts
Mazankowski Alberta Heart Institute, Edmonton, Alberta T6G2B7, Canada
Additional Information
Starting date: July 2008
Last updated: July 2, 2012
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