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Effect of Hyoscine and Promethazine on Labor Pain

Information source: Mashhad University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Labor Pain

Intervention: Hyoscine (Drug); Promethazine (Drug)

Phase: Phase 2/Phase 3

Status: Completed

Sponsored by: Mashhad University of Medical Sciences


It is always considered to shorten the duration of delivery without compromising the mother and fetus by obstetrics. Hyoscine and Promethazine are used widely in hospital and research is very limited, with conflicting results regarding the efficacy of these two drugs. So the investigators decided to compare of effect of hyoscine N-butyl bromide and Promethazine on length of active phase of the first stage of labor.

Clinical Details

Official title: Principal Investigator

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)

Primary outcome: Effect of Hyoscine and Promethazine on labor pain


Minimum age: 18 Years. Maximum age: 35 Years. Gender(s): Female.


Inclusion Criteria:

- 18-35 yrs,

- primiparous,

- having single fetus with cephalic presentation, gestational age 37-42 weeks,

- having no medical diseases,

- having no history of hospitalization due to psychological diseases,

- having no addiction to cigarette,

- having no complications during pregnancy such as hypertension,

- BMI< 26

Exclusion Criteria:

- bleeding


- use of PG or Oxytocin

- fetus distress

Locations and Contacts

Additional Information

Starting date: August 2010
Last updated: July 19, 2012

Page last updated: August 23, 2015

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