Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery
Information source: Mahidol University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Morphine
Intervention: 1 mg morphine soak in epidural oxidized cellulose (Drug); normal saline (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Mahidol University
Summary
The effect of epidural low-dose morphine-soaked microfibrillar collagen sponge in
postoperative pain control after posterior lumbar spinal surgery: a randomized,
double-blind, placebo-controlled study
Clinical Details
Official title: The Effect of Epidural Low-dose Morphine-soaked Microfibrillar Collagen Sponge in Postoperative Pain Control After Posterior Lumbar Spinal Surgery: a Randomized, Double-blind, Placebo-controlled
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
Primary outcome: VAS measurement was recorded at twenty-four hour after posterior lumbar spinal surgery then compare VAS between low-dose 1 mg morphine-soaked microfibrillar collagen sponge method with normal saline soked
Eligibility
Minimum age: 18 Years.
Maximum age: 70 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Age > 18 Yrs
- Good orientation and communication
Exclusion Criteria:
- opioids or sulfonamides allergy
- Contraindication for use
- Epidural morphine
- Selective COX 2 inhibitor
- Patient-controlled analgesia (PCA)
- ASA class > 3
- BMI ≥ 35 kg/sq. m.
- Preoperative use of opioids within 6 Wks
- Intraoperative bleeding > 1000ml
Locations and Contacts
Siriraj hospital, Bangkoknoi, Bangkok 10700, Thailand
Additional Information
Starting date: August 2012
Last updated: February 18, 2014
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