European Survey of Non-Variceal Upper Gastro Intestinal Bleeding (NVUGIB)

Condition(s) targeted: Non-variceal Upper Gastrointestinal Bleeding; Gastrointestinal Ulcer; Gastrointestinal Hemorrhage

Phase: N/A

Status: Completed

Sponsored by: AstraZeneca

Official(s) and/or principal investigator(s):
Ángel Lanas, MD, Principal Investigator, Affiliation: Hospital Clínico Universitario Lozano Blesa, Zaragoza (Spain)
Javier N Rivero, MSc, Study Director, Affiliation: Medical Department, AstraZeneca Spain

The aim of this study is to assess the current management strategies in a pan-European "real-life" setting to uncover the unmet need in this area: non-variceal gastrointestinal bleedings.

Official title: European Survey of Non-Variceal Upper Gastro Intestinal Bleeding

Study design: Observational Model: Cohort, Time Perspective: Retrospective

Primary outcome: To describe clinical outcomes associated with current strategies of endoscopic and pharmacological treatment in several European countries, in respect of bleeding continuation, rebleeding, surgery and in-hospital mortality

Secondary outcome:

To describe clinical management and how this compares across countries and Hospital types

To assess predictive factors for clinical management strategies and predictive factors related to clinical outcomes

To assess health care resource consumption in patients admitted with non-variceal upper gastrointestinal bleeding and the main drivers

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patients admitted to the hospital or inpatients with an overt non-variceal upper GI

bleed manifesting as hematemesis/coffee ground vomiting, melena, hematochezia, as well as other clinical/laboratory evidences of acute blood loss from the upper GI tract

- Evidence that an upper GI endoscopy was performed

- The complete medical record is available for study related hospitalization.

Exclusion Criteria:

- NA

Research site, Aalst, Belgium

Research site, Anderlecht, Belgium

Research site, Assebroek, Belgium

Research site, Braine L'alleud, Belgium

Research site, Brasschaat, Belgium

Research site, Brugge, Belgium

Research site, Bruxelles, Belgium

Research site, Charleroi, Belgium

Research site, Deurne, Belgium

Research site, Edegem, Belgium

Research site, Gent, Belgium

Research site, Geraardsbergen, Belgium

Research site, Hasselt, Belgium

Research site, Herentals, Belgium

Research site, Kortrijk, Belgium

Research site, Liege, Belgium

Research site, Lier, Belgium

Research site, Mechelen, Belgium

Research site, Ottignies Lln, Belgium

Research site, Tielt, Belgium

Research site, Tournai, Belgium

Research site, Turnhout, Belgium

Research site, Wetteren, Belgium

Research site, Wilrijk, Belgium

Research site, Zottegem, Belgium

Research site, Athens, Greece

Research site, Larissa, Greece

Research site, Thessaloniki, Greece

Research site, Bolzano, Italy

Research site, Cosenza, Italy

Research site, Crema, Italy

Research site, Forli, Italy

Research site, Milano, Italy

Research site, Napoli, Italy

Research site, Novara, Italy

Research site, Revenna, Italy

Research site, Roma, Italy

Research site, S. Giovanni Rotondo, Italy

Research site, Siena, Italy

Research site, Trieste, Italy

Research site, Alesund, Norway

Research site, Arendel, Norway

Research site, Bodo, Norway

Research site, Drammen, Norway

Research site, Fredrikstad, Norway

Research site, Kristiansand, Norway

Research site, Levanger, Norway

Research site, Lillehammer, Norway

Research site, Oslo, Norway

Research site, Rud, Norway

Research site, Stavanger, Norway

Research site, Tonsberg, Norway

Research site, Tromso, Norway

Research site, Trondheim, Norway

Research site, Almada, Portugal

Research site, Angra Do Heroismo, Portugal

Research site, Braga, Portugal

Research site, Caldas Da Rainha, Portugal

Research site, Castelo Branco, Portugal

Research site, Covilha, Portugal

Research site, Funchal, Portugal

Research site, Leiria, Portugal

Research site, Ponta Delgada, Portugal

Research site, Santarem, Portugal

Research site, Torres Novas, Portugal

Research site, Alcazar de San Juan, Spain

Research site, Alicante, Spain

Research site, Barcelona, Spain

Research site, Burgos, Spain

Research site, Cordoba, Spain

Research site, Huesca, Spain

Research site, La Cuesta de Arguijon, Spain

Research site, Las Palmas de Gran Canaria, Spain

Research site, Logrono, Spain

Research site, Madrid, Spain

Research site, Marbella, Spain

Research site, Murcia, Spain

Research site, Orense, Spain

Research site, Oviedo, Spain

Research site, Pamplona, Spain

Research site, Sabadell, Spain

Research site, Santiago de Compostela, Spain

Research site, Sevilla, Spain

Research site, Valencia, Spain

Research site, Zaragoza, Spain

Research site, Ankara, Turkey

Research site, Antalya, Turkey

Research site, Batman, Turkey

Research site, Bursa, Turkey

Research site, Diyarbakir, Turkey

Research site, Elazig, Turkey

Research site, Gaziantep, Turkey

Research site, Istambul, Turkey

Research site, Izmir, Turkey

Research site, Konya, Turkey

Research site, Malatya, Turkey

Research site, Mersin, Turkey

Starting date: January 2009
Last updated: December 3, 2009