Low Dose Bupivacaine Spinal for Trans Uretral Prostatectomy.
Information source: Diskapi Yildirim Beyazit Education and Research Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Benign Prostate Hyperplasia
Intervention: Heavy Bupivacaine (Drug); Isobaric Bupivacaine (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Diskapi Yildirim Beyazit Education and Research Hospital Official(s) and/or principal investigator(s):
MURAT M SAYIN, Ass. Prof, Study Director, Affiliation: Dispapi yildirim beyazit E R hospital
Summary
Spinal anesthesia, is used during the transuretheral resection of the prostate. Low dose
hyperbaric local anesthetics have been used to enhance the resolution of the spinal block.
We compared the efficacy and duration of the spinal block with two different bupivacaine
baricities.
- Group I: low dose isobaric group
- GroupII: Low dose hyperbaric group
Clinical Details
Official title: Low Dose, Low Concentration Different Baricity Bupivacaine for Transuretral Prostatectomy.
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary outcome: Spinal Block Quality
Secondary outcome: Spinal block regression
Detailed description:
Patients undergoing TURP were randomly allocated into two groups.
- Group I: Received fentanyl 20 µgr (0. 4ml),heavy bupivacaine 0. 5% (1. 5 ml)and normal
saline % 0. 9 NaCl ( 1. 1ml)
- Group II: Received fentanyl 20 µgr (0. 4 ml), plain bupivacaine 0. 5%(1. 5 ml) normal
saline 0. 9% NaCl (1. 1 mL) in total bupivacaine 0. 25% (3ml) intrathecally.
Onset and duration of the sensory block, the degree of the motor block, side - effects and
perioperative analgesic requirement assesed.
Eligibility
Minimum age: 50 Years.
Maximum age: 85 Years.
Gender(s): Male.
Criteria:
Inclusion Criteria:
- 50-85 years ASA 1-4 BENÄ°GN PROSTAT HYPERPLASÄ°
Exclusion Criteria:
- Allergy of study drugs
- Morbid obesity
- Spinal anesthesia contrindications
- Bleeding dyscrasias
Locations and Contacts
Diskapi Yildirim Beyazit Education and Research Hospital, Ankara 06610, Turkey; Not yet recruiting
Murat M Sayin, Ass. Prof, Phone: +903125962580, Email: muratsayin@hotmail.com
Reyhan POLAT, Dr, Principal Investigator
Additional Information
Related publications: Loubert C, Hallworth S, Fernando R, Columb M, Patel N, Sarang K, Sodhi V. Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study. Anesth Analg. 2011 Oct;113(4):811-7. doi: 10.1213/ANE.0b013e3182288bf2. Epub 2011 Sep 2. Kim SY, Cho JE, Hong JY, Koo BN, Kim JM, Kil HK. Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy. Br J Anaesth. 2009 Nov;103(5):750-4. doi: 10.1093/bja/aep263. Epub 2009 Sep 28.
Starting date: May 2013
Last updated: May 21, 2013
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