Protocol to Ease Acute Cephalalgia in Emergency-department
Information source: University Hospital, Grenoble
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cephalalgia
Intervention: Recommendation to use global headache treatment protocol (Other)
Phase: N/A
Status: Not yet recruiting
Sponsored by: University Hospital, Grenoble Official(s) and/or principal investigator(s): Gabriel Mirebeau, Resident, Principal Investigator, Affiliation: University Hospital, Grenoble
Overall contact: Gabriel Mirebeau, Resident, Phone: +336 85 37 18 86, Email: gmirebeau@chu-grenoble.fr
Summary
The purpose of this study is to determine if the use of a therapeutic and global protocol to
relieve cephalalgia is helpful in the emergency department of Grenoble University Hospital.
Clinical Details
Official title: Therapeutic Management of Acute Cephalalgia Before and After Use of a Therapeutic Protocol in Emergency Department
Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: Clinical improvement
Secondary outcome: Pain score on the visual analog scalePain depending on the kind of céphalalgia Impact of different kind of analgesic therapeutic Legth of the hospitalisation in emergency department Time required before medication Hospitalisation requirement
Detailed description:
Cephalalgia is a very common symptom that justifies daily appointment in emergency
department.
Analgesic support, and especially use of oxygen and care of associeted symptoms as nausea,
photophobia or phonophobia, is very dependent on the physician.
The aim of this study is to evaluate the impact of a global analgesic protocol of
céphalalgia in emergency department.
The investigators included 200 patients aged of 18 up to 55 years old coming in emergency
department for headache. Pain (Visual analogic scale), nausea, photo or phonophobia are
recorded each 15 minutes by the patient by using a self-assessment questionnaire. The final
diagnosis is recorded by the physician in charge of patient, using International Headache
Society criteria.
First 100 patients(group 1) receive usual care.
For the last 100 patients (group 2), physician in charge of patients are incited to use a
formal protocol that include: putting the patient in a quiet spot, laying down on a
stretcher, providing sound proof helmet and light blocking google, administering oxygen
therapy 15 l/min during 15 min, and administering etiological headache adapted medication
following learned society guidelines.
Comparison of the data of this 2 groups shall help us to see if the investigators actual
analgesic support of cephalalgia is efficient, and if it can be improved by this global
analgesic protocol.
Eligibility
Minimum age: 18 Years.
Maximum age: 55 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Complain about cephalalgia
- Age 28 to 55 years.
Exclusion Criteria:
- Fever > 38,0 °C
- History of breath disease, long term use of oxygen therapy, chronic obstructive
pulmonary disease, dyspnéa
- History of cranial traumatism, heart attack, cerebrovascular accident <3 month
- Inability to read or understand french.
- Pregnancy
Locations and Contacts
Gabriel Mirebeau, Resident, Phone: +336 85 37 18 86, Email: gmirebeau@chu-grenoble.fr
University Hospital, Grenoble, Isere 38700, France; Not yet recruiting Gabriel Mirebeau, Resident, Phone: +33685371886, Email: gmirebeau@chu-grenoble.fr Olivier Casez, Doctor, Phone: +33476765871, Email: ocasez@chu-grenoble.fr Gabriel Mirebeau, Resident, Principal Investigator
Additional Information
Related publications: Rasmussen BK, Jensen R, Schroll M, Olesen J. Epidemiology of headache in a general population--a prevalence study. J Clin Epidemiol. 1991;44(11):1147-57. Friedman BW, Grosberg BM. Diagnosis and management of the primary headache disorders in the emergency department setting. Emerg Med Clin North Am. 2009 Feb;27(1):71-87, viii. doi: 10.1016/j.emc.2008.09.005. Review. Haque B, Rahman KM, Hoque A, Hasan AT, Chowdhury RN, Khan SU, Alam MB, Habib M, Mohammad QD. Precipitating and relieving factors of migraine versus tension type headache. BMC Neurol. 2012 Aug 25;12:82. doi: 10.1186/1471-2377-12-82. Cohen AS, Burns B, Goadsby PJ. High-flow oxygen for treatment of cluster headache: a randomized trial. JAMA. 2009 Dec 9;302(22):2451-7. doi: 10.1001/jama.2009.1855. Ozkurt B, Cinar O, Cevik E, Acar AY, Arslan D, Eyi EY, Jay L, Yamanel L, Madsen T. Efficacy of high-flow oxygen therapy in all types of headache: a prospective, randomized, placebo-controlled trial. Am J Emerg Med. 2012 Nov;30(9):1760-4. doi: 10.1016/j.ajem.2012.02.010. Epub 2012 May 3. Matharu M. Cluster headache. BMJ Clin Evid. 2010 Feb 9;2010. pii: 1212. B. D VEYSMAN, et al. Oxygen Therapy for the tratment of undifferentiated headache in the emergency department. ClinicalTrials.gov, NCT00856232
Starting date: October 2014
Last updated: September 8, 2014
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