This Is A Multicenter, Active-Controlled Trial To Evaluate The Effects Of Celecoxib
(Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects With Juvenile Idiopathic
Arthritis
Minimum age: 2 Years.
Maximum age: 18 Years.
Gender(s): Both.
Inclusion Criteria:
- Polyarticular (both rheumatoid factor positive and rheumatoid factor
negative),oligoarticular and extended oligoarticular JIA for ≥3 months meeting the
International League of Associations for Rheumatology (ILAR) criteria for Juvenile
Idiopathic Arthritis (JIA)
- Subjects with Systemic JIA with active arthritis in at least 1 joint but without
active systemic features are eligible
- ≥2 years of age and <18 years of age prior to the Baseline visit
- Body weight ≥10 kg at the Baseline visit
- Candidate for chronic NSAID therapy in the Investigator's judgment
Exclusion Criteria:
- Psoriatic arthritis, enthesitis-related arthritis, and undifferentiated arthritis
types of JIA
- Active systemic features over the prior 12 weeks in children with systemic Juvenile
Idiopathic Arthritis (JIA)
- Subjects with psoriatic arthritis, enthesitis-related arthritis, and undifferentiated
arthritis should be excluded
- Subjects with active Systemic JIA should not be enrolled
Pfizer Investigational Site, San Jose 00000, Costa Rica
Pfizer Investigational Site, Manila 1000, Philippines
Pfizer Investigational Site, Manila 1008, Philippines
Pfizer Investigational Site, Moscow 105077, Russian Federation
Pfizer Investigational Site, Moscow 119992, Russian Federation
Pfizer Investigational Site, Smolensk 214000, Russian Federation
Pfizer Investigational Site, Smolensk 214019, Russian Federation
Pfizer Investigational Site, Belgrade 11000, Serbia
Pfizer Investigational Site, Nis 18000, Serbia
Pfizer Investigational Site, CH-1011 Lausanne, Switzerland
Pfizer Investigational Site, CH-8032 Zuerich, Switzerland
Pfizer Investigational Site, Kharkiv 61153, Ukraine
Pfizer Investigational Site, Kiev 04050, Ukraine
Pfizer Investigational Site, Kyiv 04209, Ukraine
Pfizer Investigational Site, Simferopol 95034, Ukraine
Pfizer Investigational Site, Zaporizhzhya 69063, Ukraine
Pfizer Investigational Site, Tucson, Arizona 85704, United States
Pfizer Investigational Site, Little Rock, Arkansas 72202, United States
Pfizer Investigational Site, San Diego, California 92123, United States
Pfizer Investigational Site, Hartford, Connecticut 06106, United States
Pfizer Investigational Site, Washington, District of Columbia 20010, United States
Pfizer Investigational Site, Delray Beach, Florida 33484, United States
Pfizer Investigational Site, Miami, Florida 33155-3009, United States
Pfizer Investigational Site, Pretoria, Gauteng Province 0001, South Africa
Pfizer Investigational Site, Honolulu, Hawaii 96826, United States
Pfizer Investigational Site, Honolulu, Hawaii 96813, United States
Pfizer Investigational Site, Louisville, Kentucky 40202, United States
Pfizer Investigational Site, San Borja, Lima L41, Peru
Pfizer Investigational Site, San Isidro, Lima L27, Peru
Pfizer Investigational Site, Omaha, Nebraska 68114, United States
Pfizer Investigational Site, Omaha, Nebraska 68198-5456, United States
Pfizer Investigational Site, Akron, Ohio 44308, United States
Pfizer Investigational Site, Hershey, Pennsylvania 17033, United States
Pfizer Investigational Site, Santiago, RM 8380418, Chile
Pfizer Investigational Site, Concepcion, VIII Region 4070038, Chile