DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Remifentanil for Smooth Emergence in Elderly Patients

Information source: Ajou University School of Medicine
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Drug Usage

Intervention: Remifentanil (Drug); Remifentanil (Drug); Sevoflurane (Drug)

Phase: Phase 4

Status: Not yet recruiting

Sponsored by: Ajou University School of Medicine

Official(s) and/or principal investigator(s):
Jong Yeop Kim, Principal Investigator, Affiliation: Ajou University School of Medicine

Overall contact:
Jong Yeop KIm, Phone: 82-31-219-5574, Email: kjyeop@ajou.ac.kr


Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anaesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing cough during emergence in elderly patients under sevoflurane and remifentanil anesthesia.

Clinical Details

Official title: Effect-site Concentration of Remifentanil for Preventing Cough During Emergence in Elderly Patients

Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Primary outcome: Number of cough


Minimum age: 20 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- ASA physical status I or II undergoing endoscopic sinus surgery or septoplasty under

balanced anesthesia with sevoflurane and remifentanil Exclusion Criteria:

- predicted difficult airway, body mass index > 30 kg/m2, history of obstructive sleep

apnoea chronic respiratory disease or coughing, current smokers patients angiotensin converting enzyme-inhibitors

Locations and Contacts

Jong Yeop KIm, Phone: 82-31-219-5574, Email: kjyeop@ajou.ac.kr

Additional Information

Starting date: February 2015
Last updated: January 29, 2015

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017