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Remifentanil for Smooth Emergence in Elderly Patients

Information source: Ajou University School of Medicine
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Drug Usage

Intervention: Remifentanil (Drug); Remifentanil (Drug); Sevoflurane (Drug)

Phase: Phase 4

Status: Not yet recruiting

Sponsored by: Ajou University School of Medicine

Official(s) and/or principal investigator(s):
Jong Yeop Kim, Principal Investigator, Affiliation: Ajou University School of Medicine

Overall contact:
Jong Yeop KIm, Phone: 82-31-219-5574, Email: kjyeop@ajou.ac.kr

Summary

Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anaesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing cough during emergence in elderly patients under sevoflurane and remifentanil anesthesia.

Clinical Details

Official title: Effect-site Concentration of Remifentanil for Preventing Cough During Emergence in Elderly Patients

Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Primary outcome: Number of cough

Eligibility

Minimum age: 20 Years. Maximum age: 80 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- ASA physical status I or II undergoing endoscopic sinus surgery or septoplasty under

balanced anesthesia with sevoflurane and remifentanil Exclusion Criteria:

- predicted difficult airway, body mass index > 30 kg/m2, history of obstructive sleep

apnoea chronic respiratory disease or coughing, current smokers patients angiotensin converting enzyme-inhibitors

Locations and Contacts

Jong Yeop KIm, Phone: 82-31-219-5574, Email: kjyeop@ajou.ac.kr

Additional Information

Starting date: February 2015
Last updated: January 29, 2015

Page last updated: August 23, 2015

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