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Impact of Nebivolol on Central Aortic Pressure

Information source: Creighton University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Central Aortic Pressure

Intervention: Nebivolol (Drug); Metoprolol (Drug)

Phase: N/A

Status: Withdrawn

Sponsored by: Creighton University

Official(s) and/or principal investigator(s):
Jennifer Campbell, PharmD, Principal Investigator, Affiliation: Creighton University


A randomized, cross-over, single-blind study to compare the effects of nebivolol and metoprolol on central aortic pressure and peripheral brachial pressure in patients with stable cardiovascular disease.

Clinical Details

Official title: Impact of Nebivolol on Central Aortic Pressure

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Primary outcome: Stable blood pressure


Minimum age: 45 Years. Maximum age: 75 Years. Gender(s): Both.


Inclusion Criteria:

- Subjects with history of hypertension

- Subjects who have received metoprolol for a minimum of 3 months

Exclusion Criteria:

- Patients who have had an acute myocardial infarction, coronary revascularization or

who have been hospitalized for heart failure or cardiac arrhythmia in the past 6 months

Locations and Contacts

The Cardiac Center at Creighton University, Omaha, Nebraska 68131, United States
Additional Information

Starting date: December 2009
Last updated: July 29, 2011

Page last updated: August 23, 2015

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