DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Low Dose Spinal Morphine for Post-video-assisted Thoracoscopic Surgery

Information source: Mahidol University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Video-assisted Thoracoscopic Surgery

Intervention: Morphine (Drug); control (Other)

Phase: Phase 4

Status: Recruiting

Sponsored by: Mahidol University

Official(s) and/or principal investigator(s):
Sirilak Suksompong, MD, Principal Investigator, Affiliation: Mahidol University

Overall contact:
Sirilak Suksompong, MD, Phone: 662-411-3256, Email: sirilak.suk@mahidol.ac.th


One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0. 15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control group.

Clinical Details

Official title: Low Dose Spinal Morphine for Post-video-assisted Thoracoscopic Surgery. A Pilot Study

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Total post-operative morphine requirement.

Secondary outcome: Pain after surgery


Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.


Inclusion Criteria:

- ASA (American Society of Anesthesiologist) physical status I to III,

- Undergoing elective video-assisted thoracoscopic surgery at Siriraj and Thammasart


- capable of using a patient-controlled analgesia (PCA) machine

- understanding the numeric rating scale (NRS) score for pain assessment.

Exclusion Criteria:

- history of allergy to the study drugs

- bleeding disorder

- infection of the back

- refusing spinal anesthesia

- history of cerebrovascular disease

- using postoperative ventilator support were excluded

Locations and Contacts

Sirilak Suksompong, MD, Phone: 662-411-3256, Email: sirilak.suk@mahidol.ac.th

Faculty of Medicine, Siriraj Hospital, mahidol University, Bangkok 10700, Thailand; Recruiting
Sirilak Suksompong, MD, Email: sirilak.suk@mahidol.ac.th
Sirilak Suksompong, MD, Principal Investigator
Additional Information

Starting date: February 2014
Last updated: March 19, 2014

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017