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Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus

Information source: TC Erciyes University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Postoperative Pain

Intervention: intraarticular dexamethasone (Procedure); interscalene dexamethasone (Procedure); serum phsyologic (Procedure)

Phase: Phase 4

Status: Completed

Sponsored by: TC Erciyes University

Official(s) and/or principal investigator(s):
Fatih M KURT, Resident, Principal Investigator, Affiliation: TC Erciyes University
Gülen GÜLER, Prof., Study Director, Affiliation: TC Erciyes University


the aim of this study was to investigate the analgesic efficacy of intra articular dexamethasone administration for arthroscopic shoulder surgery.

Clinical Details

Official title: Phase 4 Study of Comparison of Postoperative Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus Blockade for Arthroscopic Shoulder Surgery

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: analgesic consumption

Secondary outcome: visual analog scale

Detailed description: shoulder surgery can be very painful and interscalene brachial plexus block is the gold standard in the management of acute pain after shoulder surgery. various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexamethasone are frequently used for this purpose. dexamethasone has also been found the prolong the duration of lidocaine axillary blocks and intravenous regional anaesthesia. intraarticular administration of medicines can be used for management of joint pain and opioids , local anaesthetics and dexamethasone are used for this purpose. In addition, there are no studies available to compare the different treatment methods used in clinical practice directly.


Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Both.


Inclusion Criteria:

- between 18-65 years

- arthroscopic shoulder surgery

- no known allergies to drugs

- ASA 1-2 patients

Exclusion Criteria:

- history of diabetes

- history of chronic pain treatment

- pregnancy

- severe bronchopulmonary disease

- systemic glucocorticoid use

Locations and Contacts

Erciyes university hospital, Kayseri 38039, Turkey
Additional Information

Starting date: January 2014
Last updated: March 3, 2015

Page last updated: August 23, 2015

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