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Safety and Efficacy of Drug Combinations Against Trichuris Trichiura

Information source: DBL -Institute for Health Research and Development
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Parasitic Diseases

Intervention: albendazole (Drug); mebendazole (Drug); ivermectin (Drug); albendazole + ivermectin (Drug); mebendazole + ivermectin (Drug)

Phase: N/A

Status: Completed

Sponsored by: DBL -Institute for Health Research and Development


This randomised, controlled, double-blinded clinical study investigates the safety and efficacy of albendazole (ALB), mebendazole (MBD) and ivermectin (IVM) separately, and ALB and MBD each in combination with IVM in the treatment of Trichuris trichiura in children aged 5-14 years.

Clinical Details

Official title: Gaps in Helminth Control: Safety and Efficacy of Drug Combinations. Study on Trichuris Trichiura.

Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Primary outcome: Record adverse reactions

Secondary outcome: Efficacy of treatment


Minimum age: 5 Years. Maximum age: 15 Years. Gender(s): Both.


Inclusion Criteria:

- Those who are enrolled in class one to six

- Are infected with T. trichiura

- Whose parent consent and who are willing to participate

Exclusion Criteria:

- Those with acute and chronic diseases other than T. trichiura

- Those with a history of any serious adverse drug reactions

Locations and Contacts

Vector Control Division, Kampala, Uganda
Additional Information

Starting date: October 2007
Last updated: January 14, 2010

Page last updated: August 23, 2015

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