The Diagnosis of Penicillin/Aminopenicillin Allergy in Thailand
Information source: Chulalongkorn University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Penicillin Allergy; Aminopenicillin Allergy
Phase: N/A
Status: Recruiting
Sponsored by: Chulalongkorn University Official(s) and/or principal investigator(s):
Jettanong Klaewsongkram, MD, Principal Investigator, Affiliation: Chulalongkorn University
Overall contact:
Jettanong Klaewsongkram, MD, Phone: 02-2564152, Email: Jettanong.K@chula.ac.th
Summary
The true prevalence of drug allergy in patients with a history of penicillin/aminopenicillin
allergy will be determined by using commercially available standard skin test reagents and
the diagnostic agents available in Thailand. We hypothesize that only minority of patients
with such a history are truly allergic.
Clinical Details
Official title: The Optimized Diagnostic Methods for the Confirmation of Penicillin/Aminopenicillin Allergy in Thailand
Study design: Observational Model: Cohort, Time Perspective: Cross-Sectional
Primary outcome: The true prevalence of penicillin/aminopenicillin allergy
Secondary outcome: The diagnostic values of currently used skin test reagents and drug-specific IgE measurement
Detailed description:
Patients with a history of an immediate reaction to penicillin/aminopenicillin will be
evaluated by the standard skin test reagents (major and minor determinants of penicillin,
amoxicillin, and clavulanic if applicable).
Diagnostic values of the measurement of specific IgE to penicillin/aminopenicillin and skin
test reagents currently available in Thailand will be comparatively analyzed with the
standard skin test reagents.
Eligibility
Minimum age: 7 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients with a history of an immediate reaction to penicillin/aminopenicillin
Exclusion Criteria:
- Being pregnant
- Having serious medical illnesses
- Have a history of severe non-immediate reaction to penicillin/aminopenicillin
Locations and Contacts
Jettanong Klaewsongkram, MD, Phone: 02-2564152, Email: Jettanong.K@chula.ac.th
Chulalongkorn University, Bangkok 10330, Thailand; Recruiting
Jettanong Klaewsongkram, MD, Phone: 02-2564152, Email: Jettanong.K@chula.ac.th
Jettanong Klaewsongkram, MD, Principal Investigator
Additional Information
Starting date: November 2012
Last updated: October 20, 2014
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