Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation
Information source: Inje University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Psychomotor Agitation
Intervention: Midazolam (Drug); Ketamine (Drug)
Phase: N/A
Status: Completed
Sponsored by: Inje University Official(s) and/or principal investigator(s):
Kihwa Lee, MD, Study Chair, Affiliation: Haeundae paik hospital, inje university
Summary
Compare the effects of intravenous midazolam and ketamine on emergence agitation after
sevoflurane anesthesia
Clinical Details
Official title: Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation : a Randomized Controlled Trial
Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Primary outcome: Emergence Agitation
Detailed description:
Emergence agitation is self-limiting aggressive behavior that develops in the early period
of awakening from anesthesia. A high level of preoperative anxiety is a risk factor for
emergence agitation using Aono's four-point scale. Midazolam and ketamine was administered
to the patients to decrease of preoperative anxiety. We aimed to compare the emergence
agitation between midazolam group and ketamine group.
Eligibility
Minimum age: 2 Years.
Maximum age: 6 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- American society of anesthesiologists physical status 1-2 aged 2-6 years old, who
were scheduled to undergo ophthalmic surgery (<2hr)
Exclusion Criteria:
- children with central nervous system disorders,history of allergy to the study drugs
(midazolam and ketamine), history of recent respiratory tract infection
Locations and Contacts
Additional Information
Starting date: January 2013
Last updated: October 9, 2014
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