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DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

Information source: University Hospital Case Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Postoperative Ecchymosis

Intervention: DDAVP (Drug)

Phase: Phase 2

Status: Not yet recruiting

Sponsored by: University Hospital Case Medical Center

Official(s) and/or principal investigator(s):
Bahman Guyuron, MD, Principal Investigator, Affiliation: University Hospitals

Summary

This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders. It works by activating molecules in the blood stream called platelets that promote clotting. In the study, participants who are have cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive medication. Photographs taken before and shortly after surgery will be evaluated for the amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are not eligible to participate.

Clinical Details

Official title: A Prospective Randomized Trial for the Use of DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty.

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Reduction in Ecchymosis and Swelling

Secondary outcome: Patient Behavior Factors

Eligibility

Minimum age: 18 Years. Maximum age: 80 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Undergoing Rhinoplasty where nasal bone osteotomy is necessary

Exclusion Criteria:

- Heart Disease

- Renal Disease with decreased GFR

- Liver Disease

Locations and Contacts

Lyndhurst Surgery Center, Lyndhurst, Ohio 44124, United States; Not yet recruiting
Bahman Guyuron, MD, Phone: 440-461-7999, Email: bahman.guyuron@uhhospitals.org
Bahman Guyuron, MD, Principal Investigator
Additional Information

Starting date: December 2013
Last updated: November 14, 2013

Page last updated: August 23, 2015

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