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Imaging the Dopamine Systems in Bulimia Nervosa

Information source: New York State Psychiatric Institute
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Eating Disorders

Phase: N/A

Status: Completed

Sponsored by: New York State Psychiatric Institute

Summary

This study will use positron emission tomography imaging to investigate the dopamine systems in people with bulimia nervosa.

Clinical Details

Official title: Imaging the Dopamine Systems in Bulimia Nervosa

Study design: Observational Model: Case Control, Time Perspective: Cross-Sectional

Primary outcome:

D2 receptor density

DA release in the striatum

Eligibility

Minimum age: 18 Years. Maximum age: 45 Years. Gender(s): Female.

Criteria:

Inclusion Criteria: Participants with BN:

- Meets DSM-IV criteria for BN

- Sufficiently medically and psychiatrically stable to participate in research

Health Control Participants:

- No current or past psychiatric illness

- Between 80% and 120% of ideal body weight

Exclusion Criteria: All participants:

- Current use of psychotropic medication such as anti psychotics or antidepressants

- Pregnant or breastfeeding

- history of substance abuse

- Significant medical illness

- High blood pressure (resting systolic blood pressure greater than 150mmHg and

diastolic blood pressure greater that 90 mmHg)

- Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic

disorder as defined by DSM-IV

- Metal implants or paramagnetic objects contained within the body that may interfere

with the MRI scan, as determined in consultation with a neuroradiologist and according to specified reference book guidelines

- Exposed to radiation in the workplace or has had a nuclear medicine procedure during

the 1 year before study entry

- Previous adverse reaction to psycho stimulants

Locations and Contacts

New York State Psychiatric Institute, New York, New York 10032, United States
Additional Information

Starting date: January 2008
Last updated: August 14, 2014

Page last updated: August 23, 2015

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