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Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery

Information source: Stanford University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Glaucoma

Intervention: Triamcinolone injection, sub-tenon (Drug)

Phase: N/A

Status: Recruiting

Sponsored by: Stanford University

Summary

Determine efficacy of sub tenon kenalog injections for post-operative management of trabeculectomy procedures.

Clinical Details

Official title: Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Primary outcome: Intraocular pressure

Secondary outcome: visual field progression, need for further surgery or medications

Detailed description: Postoperative sub-Tenon Triamcinolone Acetonide in glaucoma filtering surgery Objectives: Trabeculectomy is a surgical procedure designed to reduce internal eye pressure by draining fluid from within the eye to the sub-conjunctival (superficial eye lining) space. Scar formation from conjunctival and Tenon's capsule fibroblast proliferation represents the most common cause of failure of trabeculectomies. A number of drugs have been use to prevent failure of trabeculectomies from the scarring process including intraoperative mitomycin C (MMC) and preoperative Triamcinalone Acetonide (TA). Over the past several years, intraoperative MMC has become a preferred method of preventing scar formation. This study looks to determine in a prospective, double-blind, randomized method the long-term efficacy and safety of MMC with postoperative TA compared to the standard practice of intraoperative MMC with postoperative prednisolone acetate drops in preventing scar related failures of trabeculectomies.

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria: Trabeculectomy surgery patient, age 18 or older - Exclusion

Criteria: Pregnant, nursing, age less than 18, known allergy to medication being studied

Locations and Contacts

Santa Clara valley Medical Center, San Jose, California 95128, United States; Recruiting
Christopher J Engelman, MD, Phone: 408-885-6770, Email: engelman@stanford.edu

Stanford University School of Medicine, Stanford, California 94305, United States; Recruiting
Christopher J Engelman, MD, Phone: 408-885-6770, Email: engelman@stanford.edu
Christopher James Engelman, Principal Investigator

Additional Information


Last updated: February 22, 2008

Page last updated: August 23, 2015

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