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Comparison of Efficacy of Ivabradine Versus Metoprolol

Information source: Phramongkutklao College of Medicine and Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Coronary Artery Disease

Intervention: Ivabradine and Metoprolol (Drug)

Phase: Phase 4

Status: Not yet recruiting

Sponsored by: Col. Suthee Panichkul

Official(s) and/or principal investigator(s):
Purich - Surunchupakorn, M.D., Principal Investigator, Affiliation: Phramongkutklao College of Medicine and Hospital

Overall contact:
Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com


Ivabradine may be better than Metoprolol for controlling heart rate before Coronary CTA.

Clinical Details

Official title: Comparison of Efficacy and Safety of Ivabradine Versus Metoprolol for Controlling Heart Rate Prior to 640-Slice Computed Tomographic Angiography in Elective Patients

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Diagnostic

Primary outcome: Heart rate of patient before CT coronary

Secondary outcome: safety and side effect of Metoprolol and Ivabradine


Minimum age: 18 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- elective patient on scheduled for 640 slices CT coronary at Phramonkutklao hospital

- Resting heart rate > 70 BPM

- age > 18 years and informed consent

Exclusion Criteria:

- Heart rate > 100 BPM

- BP <100/60 mmHg

- recent congestive heart failure in 1 mo.

- SA node, AV node disease and AF

- on permanent pacemaker

- CrCL < 15ml/min. , AST or ALT > 3x UNL

- on HR reducing drug such as diltiazem, verapamil, digitalis

- contraindication for ivabradine or metoprolol

Locations and Contacts

Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com

Phramonkutklao Hospital, Bangkok 10400, Thailand; Not yet recruiting
Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com
Purich - Surunchupakorn, M.D., Principal Investigator
Additional Information

Starting date: December 2014
Last updated: October 27, 2014

Page last updated: August 23, 2015

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