Comparison of Efficacy of Ivabradine Versus Metoprolol
Information source: Phramongkutklao College of Medicine and Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Coronary Artery Disease
Intervention: Ivabradine and Metoprolol (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Col. Suthee Panichkul Official(s) and/or principal investigator(s): Purich - Surunchupakorn, M.D., Principal Investigator, Affiliation: Phramongkutklao College of Medicine and Hospital
Overall contact: Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com
Summary
Ivabradine may be better than Metoprolol for controlling heart rate before Coronary CTA.
Clinical Details
Official title: Comparison of Efficacy and Safety of Ivabradine Versus Metoprolol for Controlling Heart Rate Prior to 640-Slice Computed Tomographic Angiography in Elective Patients
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Diagnostic
Primary outcome: Heart rate of patient before CT coronary
Secondary outcome: safety and side effect of Metoprolol and Ivabradine
Eligibility
Minimum age: 18 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- elective patient on scheduled for 640 slices CT coronary at Phramonkutklao hospital
- Resting heart rate > 70 BPM
- age > 18 years and informed consent
Exclusion Criteria:
- Heart rate > 100 BPM
- BP <100/60 mmHg
- recent congestive heart failure in 1 mo.
- SA node, AV node disease and AF
- on permanent pacemaker
- CrCL < 15ml/min. , AST or ALT > 3x UNL
- on HR reducing drug such as diltiazem, verapamil, digitalis
- contraindication for ivabradine or metoprolol
Locations and Contacts
Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com
Phramonkutklao Hospital, Bangkok 10400, Thailand; Not yet recruiting Purich Surunchupakorn, M.D., Phone: 081-988-7390, Email: winnermd57@gmail.com Purich - Surunchupakorn, M.D., Principal Investigator
Additional Information
Starting date: December 2014
Last updated: October 27, 2014
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