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Economic Impact of Switching From Metoprolol to Nebivolol for Hypertension Treatment

Information source: Forest Laboratories
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Hypertension

Intervention: Metoprolol (Drug); Nebivolol (Drug)

Phase: N/A

Status: Active, not recruiting

Sponsored by: Forest Laboratories

Official(s) and/or principal investigator(s):
Stephanie Chen, PhD, Study Director, Affiliation: Forest Laboratories

Summary

This is a retrospective data analysis of patients with high blood pressure (hypertension) who took metoprolol for a minimum of 6 months who then switched to taking nebivolol for a minimum of 6 month to treat hypertension. These patients will be identified from a large medical claims database. This study tests the hypothesis (alternative, higher or lower) that average patient monthly health care administrative cost changes after switching from metoprolol to nebivolol.

Clinical Details

Official title: Economic Impact of Switching From Metoprolol to Nebivolol for Hypertension Treatment: A Retrospective Database Analysis

Study design: Observational Model: Cohort, Time Perspective: Retrospective

Primary outcome: Patient monthly health care cost

Secondary outcome:

Number of monthly out-patient visits

Monthly Emergency Room visits per patient

Monthly hospitalizations per patient

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Be at least 18 years old at initiation of metoprolol (or first date on metoprolol

treatment between 2007 and 2011)

- Had one or more inpatient or outpatient claims with a primary or non-primary

diagnosis of hypertension (ICD-9-CM 401. xx-405. xx)

- Received nebivolol treatment continuously (defined as supply gap <30 days) for at

least 6 months after initiation

- Received metoprolol treatment continuously for at least 6 months prior to switching

to (initiation of) nebivolol (defined as metoprolol was discontinued whereas a prescription for nebivolol was filled)

- Had at least 12 months of continuous enrollment (as verified using enrollment file):

6 month prior to nebivolol initiation and 6 months following nebivolol initiation.

Locations and Contacts

Forest Investigative Site 0, Jersey City, New Jersey 07311, United States
Additional Information

Starting date: October 2012
Last updated: December 26, 2012

Page last updated: August 23, 2015

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