The Impact of Obesity on Nonsurgical Periodontal Therapy
Information source: Federal University of Rio Grande do Sul
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Periodontitis; Periodontal Diseases; Obesity
Intervention: Metronidazole (Drug); Placebo (Drug); Scaling and root planning (Procedure)
Phase: N/A
Status: Recruiting
Sponsored by: Federal University of Rio Grande do Sul Official(s) and/or principal investigator(s): Cassiano K Rosing, DDS, PhD, Principal Investigator, Affiliation: Federal University of Rio Grande do Sul Cristiano Susin, DDS, PhD, Principal Investigator, Affiliation: Medical College of Georgia School of Dentistry
Overall contact: Eduardo J Gaio, DDS, Phone: 55 51 9252 4577, Email: dudagaio@hotmail.com
Summary
The purpose of this study is to investigate the effect that obesity may have on the
nonsurgical treatment (with and without the adjunct use of metronidazole) of destructive
periodontal diseases (chronic periodontitis).
Clinical Details
Official title: The Impact of Obesity on Nonsurgical Periodontal Treatment of Destructive Periodontal Diseases
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
Primary outcome: Probing depth
Secondary outcome: Attachment level
Detailed description:
Normal weight (BMI 18. 5-24. 9 kg/m2) and obese (BMI >30 kg/m2) women will be randomly
assigned to two nonsurgical periodontal treatments:
1. scaling and root planing + placebo
2. scaling and root planing + metronidazole
Eligibility
Minimum age: 35 Years.
Maximum age: 55 Years.
Gender(s): Female.
Criteria:
Inclusion Criteria:
- Normal weight or obese (according to BMI)
- nonsmokers or former smokers (3 or more years)
- no systemic diseases that may affect periodontal treatment (diabetes, osteoporosis,
steroid use)
- have 10 teeth present
- have at least 2 teeth with probing depth 6+mm and attachment loss 4+mm
Exclusion Criteria:
- Pregnancy
- Development of diabetes or other conditions that may impair periodontal healing
Locations and Contacts
Eduardo J Gaio, DDS, Phone: 55 51 9252 4577, Email: dudagaio@hotmail.com
Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90035-003, Brazil; Recruiting Eduardo J Gaio, DDS, Phone: 55 51 9252 4577 Juliano Cavagni, DDS, Phone: 55 54 8111 9440, Email: jcavagni@hotmail.com Cassiano K Rosing, DDS, PhD, Principal Investigator
Additional Information
Starting date: August 2009
Last updated: July 28, 2011
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