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The Impact of Obesity on Nonsurgical Periodontal Therapy

Information source: Federal University of Rio Grande do Sul
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Periodontitis; Periodontal Diseases; Obesity

Intervention: Metronidazole (Drug); Placebo (Drug); Scaling and root planning (Procedure)

Phase: N/A

Status: Recruiting

Sponsored by: Federal University of Rio Grande do Sul

Official(s) and/or principal investigator(s):
Cassiano K Rosing, DDS, PhD, Principal Investigator, Affiliation: Federal University of Rio Grande do Sul
Cristiano Susin, DDS, PhD, Principal Investigator, Affiliation: Medical College of Georgia School of Dentistry

Overall contact:
Eduardo J Gaio, DDS, Phone: 55 51 9252 4577, Email: dudagaio@hotmail.com

Summary

The purpose of this study is to investigate the effect that obesity may have on the nonsurgical treatment (with and without the adjunct use of metronidazole) of destructive periodontal diseases (chronic periodontitis).

Clinical Details

Official title: The Impact of Obesity on Nonsurgical Periodontal Treatment of Destructive Periodontal Diseases

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Primary outcome: Probing depth

Secondary outcome: Attachment level

Detailed description: Normal weight (BMI 18. 5-24. 9 kg/m2) and obese (BMI >30 kg/m2) women will be randomly assigned to two nonsurgical periodontal treatments: 1. scaling and root planing + placebo 2. scaling and root planing + metronidazole

Eligibility

Minimum age: 35 Years. Maximum age: 55 Years. Gender(s): Female.

Criteria:

Inclusion Criteria:

- Normal weight or obese (according to BMI)

- nonsmokers or former smokers (3 or more years)

- no systemic diseases that may affect periodontal treatment (diabetes, osteoporosis,

steroid use)

- have 10 teeth present

- have at least 2 teeth with probing depth 6+mm and attachment loss 4+mm

Exclusion Criteria:

- Pregnancy

- Development of diabetes or other conditions that may impair periodontal healing

Locations and Contacts

Eduardo J Gaio, DDS, Phone: 55 51 9252 4577, Email: dudagaio@hotmail.com

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90035-003, Brazil; Recruiting
Eduardo J Gaio, DDS, Phone: 55 51 9252 4577
Juliano Cavagni, DDS, Phone: 55 54 8111 9440, Email: jcavagni@hotmail.com
Cassiano K Rosing, DDS, PhD, Principal Investigator
Additional Information

Starting date: August 2009
Last updated: July 28, 2011

Page last updated: August 23, 2015

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