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Marcaine Use in Laparoscopic Gynecological Surgery

Information source: Weill Medical College of Cornell University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Post-operative Pain

Intervention: Marcaine- 0.25% (Drug); Marcaine 0.25%. (Drug)

Phase: N/A

Status: Terminated

Sponsored by: Weill Medical College of Cornell University

Official(s) and/or principal investigator(s):
Glenn Schattman, MD, Principal Investigator, Affiliation: Weill Medical College of Cornell


The purpose of this trial is to compare incisional pain in patients receiving pre-incisional versus post operative Marcaine injection.

Clinical Details

Official title: A Comparative Trial of Marcaine Administration in Laparoscopic Gynecologic Surgery Using Either a Pre- or Post-operative Injection.

Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Primary outcome: Pain level.

Secondary outcome: Use of pain medication

Detailed description: Post-operative pain control is a key component of a patient's experience with surgery. In laparoscopic surgery, small (5 to 12mm) incisions are made, usually at the umbilicus and/on at either side of the lower abdomen, to allow insertion of a laparoscopic camera ("scope") and various laparoscopic instruments. The advantages for the patient of this approach compared to conventional open surgery include faster recovery with a significantly shorter hospital stay, less pain and less requirements for pain medication with a better cosmetic outcome. In many cases, the patient will go home within 24 hours of surgery. Many laparoscopic surgeons administer local anesthesia at the incision sites to assist in post-operative pain control. The best method for administration of the local anesthetic for optimal pain relief remains unclear. Some research has demonstrated that perhaps preemptive administration of local anesthetic improves post-operative pain control although in these studies, differences in patient populations and perception of pain between different patients makes comparison difficult. Optimizing analgesia protocols would benefit patients resulting in better pain relief and less use of narcotic analgesics with their associated side effects.


Minimum age: 18 Years. Maximum age: 50 Years. Gender(s): Female.


Inclusion Criteria:

- • Ages 18-50

- BMI 20-35

- Gynecologic ambulatory cases only

- Total of 3 incisions, with left and right incisions both being 5mm-10mm in size

- Not taking pain medications prior to surgery

- Length of surgery up to 3 hours

- PACU stay up to 6 hours

- Willing and able to sign informed consent

Exclusion Criteria:

- • Age or BMI out of range

- Surgery longer than 3 hours or PACU stay longer than 6 hours

- patients with chronic pelvic pain

- Oncologic cases

- Pregnant patients

Locations and Contacts

Weill Cornell Medical College, New York, New York 10021, United States
Additional Information

Starting date: June 2010
Last updated: January 6, 2014

Page last updated: August 23, 2015

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