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Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine

Information source: Frederikssunds Hospital, Denmark
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Spinal Anesthesia

Intervention: Lidocaine (Drug); bupivacaine (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Frederikssunds Hospital, Denmark

Official(s) and/or principal investigator(s):
Jon Jacobsen, M.D., Principal Investigator, Affiliation: Frederikssunds Hospital, Denmark


The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.

Clinical Details

Official title: Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine?

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Duration of spinal blockade

Secondary outcome: Time to fulfillment of discharge criteria from the hospital.


Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Both.


Inclusion Criteria:

- The patient want spinal anaesthesia

- No contradictions against spinal anaesthesia

- Healthy people (ASA-score 1 or 2)

- Body mass index < 35 and between 155 and 190 cm

Exclusion Criteria:

- Known allergic reactions to planned drugs

- Neurologic disturbances

- Diabetes

Locations and Contacts

Dep. of anesthesiology, Hospital of Frederikssund, Frederikssund 3600, Denmark

Jon Jacobsen, Frederikssund DK 3600, Denmark

Additional Information

Starting date: November 2009
Last updated: May 7, 2015

Page last updated: August 23, 2015

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