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Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus Blockade

Information source: TC Erciyes University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Sequelae of Fracture of Forearm and Upper Arm

Intervention: dexmedetomidine (Drug); bupivacaine (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: TC Erciyes University

Official(s) and/or principal investigator(s):
Recep Aksu, Study Director, Affiliation: Ass.Prof.


the aim of this study was effect of the addition of dexmedetomidine to bupivacaine during supraclavicular brachial plexus blockade for forearm surgery, by low doses bupivacaine providing prolonged analgesia after surgery.

Clinical Details

Official title: Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus Blockade for Forearm Surgery.

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: the duration of sensorial block

Secondary outcome: the first time analgesic required

Detailed description: Anaesthesia for surgeries to the upper extremity commonly is provided using brachial plexus anaesthesia. Various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexmedetomidine are frequently used for this purpose. this study was conducted to compare the effects of adding dexmedetomidine to local anaesthetics in the supraclavicular brachial plexus block by using nerve stimulators and ultrasonography guided. dexmedetomidine has also been found the prolong the duration of bupivacaine infraclavicular brachial plexus block.


Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Both.


Inclusion Criteria:

- 18-65 age

- unwanted general anaesthesia

- ASA 1-2

- single forearm, arm surgery

Exclusion Criteria:

- major psychiatric problems

- major neurologic deficits

- coagulopathy

- drug allergies

- chronic analgesic used

Locations and Contacts

Erciyes University Medical Faculty, Kayseri 38039, Turkey
Additional Information

Starting date: January 2014
Last updated: November 7, 2014

Page last updated: August 23, 2015

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