Effect of the Salbutamol on Mechanical Properties of Respiratory System
Information source: Rio de Janeiro State University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Smoking; Airway Obstruction
Intervention: Salbutamol sulphate (Drug)
Phase: N/A
Status: Recruiting
Sponsored by: Rio de Janeiro State University Official(s) and/or principal investigator(s): Gerusa M Costa, MSc, Principal Investigator, Affiliation: State University of Rio de Janeiro Pedro L Melo, PhD, Study Director, Affiliation: Laboratory biomedical instrumentation
Overall contact: Agnaldo J Lopes, PhD, Phone: 55+(21) 98536162, Email: phel.lop@uol.com.br
Summary
The aim of this study is to assess the bronchodilator response of salbutamol on respiratory
mechanics of healthy individuals, smokers and COPD with varying degrees of airway
obstruction.
Clinical Details
Official title: Effect of the Use of Salbutamol on the Mechanical Properties of the Respiratory System of Healthy Individuals, Smokers and COPD Patients
Study design: Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
Primary outcome: Respiratory function test
Secondary outcome: Salbutamol
Detailed description:
Clinical evaluation will be conducted and anthropometric measurements, then the pulmonary
function tests: forced oscillation technique (FOT), whole body plethysmography, spirometry
and-administration of salbutamol aerosol for assessment of bronchodilator response. After 20
minutes, the individual will be evaluated again following the same sequence.
Eligibility
Minimum age: 40 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- healthy individuals, smokers and patients with chronic obstructive pulmonary disease.
Exclusion Criteria:
- healthy subjects: no history of smoking respiratory infection and disease respiratory
- smokers and chronic obstructive pulmonary disease patients: asthma and other
respiratory diseases.
Locations and Contacts
Agnaldo J Lopes, PhD, Phone: 55+(21) 98536162, Email: phel.lop@uol.com.br
Laboratory biomedical instrumentation - State University of Rio de Janeiro, Rio de Janeiro 20550013, Brazil; Recruiting Gerusa M Costa, MSc, Principal Investigator
Additional Information
http://www.ncbi.nlm.nih.gov/pubmed?term=gerusa%20maritimo%20da%20costa
Starting date: June 2011
Last updated: January 31, 2012
|