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High-resolution Computed Tomography (HRCT) Evaluation of Airway Distensibility in Lung Transplant Recipients

Information source: The University of Texas Medical Branch, Galveston
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Lung Transplant

Phase: N/A

Status: Recruiting

Sponsored by: The University of Texas Medical Branch, Galveston

Official(s) and/or principal investigator(s):
Alexander G Duarte, MD, Principal Investigator, Affiliation: University of Texas

Overall contact:
Alexander G Duarte, MD, Phone: 409-772-2436, Email: aduarte@utmb.edu

Summary

Lung and heart-lung recipients at the University of Texas Medical Branch who have participated in the "Assessment of Cough Reflex in Lung Transplant Recipients" study who meet the specific study inclusion/exclusion criteria will have one study visit where they will undergo lung volume measurements, followed by high resolution CT scan of the lungs within 2 hours. After the initial CT scan, patients will be given a standard dose of Atrovent, followed thirty minutes later by repeat lung volume measurements and CT scan.

Clinical Details

Official title: High Resolution Computed Tomographic Evaluation of Airway Distensibility in Lung Transplant Recipients: A Pilot Study

Study design: Observational Model: Cohort, Time Perspective: Prospective

Primary outcome: Spirometry changes

Secondary outcome: Lung volumes

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- lung transplant recipients >18 years of age

- at least 12 months or greater from time of transplantation

Exclusion Criteria:

- hemodynamic instability

- hypoxemia

- pneumonia

- moderate or large pleural effusion

- clinical evidence of acute rejection

Locations and Contacts

Alexander G Duarte, MD, Phone: 409-772-2436, Email: aduarte@utmb.edu

University of Texas Medical Branch, Galveston, Texas 77555, United States; Recruiting
Alexander G Duarte, MD, Phone: 409-772-2436, Email: aduarte@utmb.edu
Additional Information

Starting date: August 2007
Last updated: May 27, 2014

Page last updated: August 20, 2015

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